vessel anatomy - heximer Flashcards

1
Q

what controls blood going into caps.

A

pre-capillary sphincter

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2
Q

what is blood volume distributions in body

A

large art - 15-20%
small arteriole -3%
veins - 65-70%

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3
Q

what are 2 most important properties of veins

A
  1. compliance

2. resistance

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4
Q

what is compliance

A

V/P

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5
Q

what determines resitance

A

poiseuilles law

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6
Q

what part of venous system has most area

A

caps.

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7
Q

where is blood velocity the slowest

A

caps.

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8
Q

what are 2 main types of caps. and where are they

A
  1. tight - most of body

2. fenestrated - liver etc. - let more out

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9
Q

what determines net pressure flow out of caps

A

hydrostatic pressure and osmotic pressure

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10
Q

what is muscle in art and vein

A

smooth muslce

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11
Q

what is diff between striate and smooth muscle in structure

A

striated - organized

smooth - no ultrastructure

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12
Q

what is diff between striate and smooth muscle in activation

A

striated - direct Ca activation

smooth - Ca activation via enzyme cascade

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13
Q

what is diff between striate and smooth muscle in activation on/off

A

striated - on off mech

smooth - graded actitvity

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14
Q

what is diff between striate and smooth muscle in E requirement

A

striated - high

smooth - low

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15
Q

what is diff between striate and smooth muscle in contracted length

A

striated - 4/5

smooth - 1/5

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16
Q

what does smooth muscle GPCR activate

A

PLC (phospholipase)

17
Q

what does PLC catalyze

A

IP-3 on SR to release Ca

18
Q

what is the site on myosin that is activated by P

A

myosin light chain 2 -regulatory light chain

19
Q

what are two regulators of myosin working in smooth muscle

A

MLC kinase - on

MLC phosphotase - off

20
Q

how is MLCK activated

A

Ca + caldesmon

21
Q

how is latch state created

A

MLC phosphotase takes P off while attached