General Flashcards
4 functions of blood
- transport
- temp and pH regulation
- protect agains infection
- coagulation
Main components of blood (%)
- plasma (55)
- WBC (<1)
- RBC (45)
Formula for hemoclobin
3x hematocrit
define mean cell volume
how big an RBC are
define mean cell width
degree of differences between sizes of cells
features of erythrocyte
- discoid shape
2. contains heme and globin
RBC lifespan
120 days
define good central pallor of RBC
1/3, 1/3, 1/3
define anemia
decreased hemoglobin - less O2 cap.
causes of anemia (3)
- decr. production
- incr. destruction
- dilution sequestration
define polycythemia
too many RBCs
symptoms of polycythemia
headache, plethora, shortness of breath, numbeness
Types of leukocytes
- Neutrophils
- Eosonophils
- Basophils
- Lymphocytes
- Monocytes
Features of neutrophils
slightly bigger than RBCs
2-5 lobe nucleus
granules in cytoplasm
function of neutrophil
main infection fighter
life of neutrophils
5 days
consequence of neutropenia
bacterial infections
causes of neutrophilia (3)
- demarginalization
- reactive (incr. production)
- malignancy
features of eosonophils
2-3 lobes
large granules
localize to tissues
functions of eosonophils (3)
- cytotoxic
- inflammatory reactions
- hypersensitivity reactions
causes on eosonophilia (3)
- allergic reactions
- parasitic reactions
- malignancy
features of basophils
large black granules
3 granulocytes
- neutophils
- eosonophils
- basophils
features of lymphocytes
mononuclear
scant bule cytoplasm
nucleus the size of RBC
2 main functions of lymphocytes
- viral surveillance - antibodies
2. between lymphoid tissues and systemic circulation
2 main types of lymhocytes
- B - antigen receptors and antibodies
2. T - CD4, CD8, natural killer
causes of lymphopenia (3)
- decr. production
- incr. destruction
- dilution sequestration
causes of lymphocytosis
- viral
- stress
- smoking
- malignancy
features of monocytes
double size of RBC
horseshoe nucleus
fine reddish granules
migrate to tissues
2 differnent end cells of monocytes
- macrophages
2. dendritic cells
cause if monocytosis
- chronic infection
- chronic inflammation
- malignancy
featues of platelets (thrombocytes)
very small
fine purple granules
causes of thrombocytosis
- reactive
- bone marrow malignancy
- redistributive (post-splenectomy)