Depression Flashcards
**what causes the largerst global burden of disease
depression
**features of depression episode
M - mood S - sleep I - interest G - guilt E - energy C - concentration A - appetitie/weight P - psychomotor retarded S - suicidal
what is episode vs. disorder
- episode is deiscrete period
- MDE can be part of another disorder
- MDD requires it not being better explianed by another disorder
DDx for depression
- bipolar
- persistent depressive dis
- premenstrual DD
- substance induced DD
- DD due to GMC
- adjustment with depressed mood
- bereavement
def. bipolar
type 1 - manic episode
type 2 - hypomania and MDE required - no mania allowed
def. persistent DD
depression for most of the day, for more days than not for 2 years
def. PMDD
mood in week before period and then goes away
- impariment
3 keys to substance induced MD
- occurs after substance
- persists after substance stopped
- can be meds
what is adjustment disorder with depressed mood
Sx that come within 3 months of a stressor and go away within 6 months
- don’t meet MDE requirements
lifetime prev of depression
10-20%
what is trigger for first and subsequent depression
1st - multiple stressors
after - don’t always seem to have stressors - at risk
what are 3 major monaamines of depression
- 5HT
- NE
- DA
what are treatments for types of depresison
mild/mod - CBT and IPT
severe - drugs +/- therapy
best with both
6 main classes of anti-dep
SSRI SNRI SDRI NaSSA TCA MAOi
SSRI SE
HANDS Headache Anxiety Nausea Diarrhea SEX and sleep
