Kidney CA Flashcards

1
Q

2 main benign renal lesions

A
  1. renal cyst

2. angiolyolipoma (AML)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are renal cysts

A

fluid filled sac in renal parenchyma

  • common
  • M>F
  • increase with age
  • most benign, some have malig potential
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is needed to diagnose renal cysts

A

radiological Dx

  • US is good most of the time
  • CT/MR for complex issues
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

4 features of a simple renal cyst on US

A
  1. anechoiuc- dark
  2. well defined wall
  3. posterior acoustic enhancement
  4. no internal calcification or solid
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

3 features of simple cyst on CT

A
  1. homogenous
  2. low (water) density
  3. no internal enhancement
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

3 features of simple cyst on MR

A
  1. homogenous
  2. follows fluid on all sequences (T1 dark, T2 bright)
  3. no internal enhancements
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is classification system for cysts

A
Bosniak system - radiologic based
1. simple - no malig
2. mild complex - 1-2% malig
2F. complex - 10-15 malig
3. sig. complex - 40-50 malig
4. CA until proven otherwise
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is follow up for classes

A

1 and 2 - no follow-up
2F - imaging surveillace
3 and 4 - surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what are features of type 1

A
  • simple benign
  • thin walled
  • water density
  • so septa or calcifications
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

features of type 2

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

features of type 3

A
  • mural or septal thinkening

- both benign and malig. lesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

featues of type 4

A

fulfills type 3

  • clearly malig
  • enhancing soft tissue component indep. of cyst wall or septa
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

features of 2F

A
  • F for follow-up
  • well marginated
  • may contain multiple thin walled septa
  • minimal mural or septal thinkening
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is AML

A
  • benign tumor with variable amounts of blood vessels, muscle, or fat
  • f>M, rare before puberty
  • most sporadic
  • usually asymptomatic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is path of AML

A
  • see all three elements

- + HMB stain, - cytokeratin stain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how to diagnose AML

A

US is generally enough

- CT or MR if issues

17
Q

4 features of AML on US

A
  1. sharp margins
  2. hyperechoic
  3. homo exotexture
  4. no calcif
18
Q

4 features of AML on CT

A
  1. high spatial resolution
  2. mixed density lesion
  3. no calcif.
  4. no lymphadenopathy
19
Q

3 features of AML on MR

A
  1. high soft tissue contrast
  2. mixed compostiion - fat, muscle, vessels
  3. bulk fat
20
Q

2 possible pitfalls for imaging AML

A
  1. RCC may be echogenic on US

2. some AML with minimal fat

21
Q

mgmt options

A
  1. surveillance for most
  2. selective angioembolization
  3. Nx - partial or full
22
Q

indication for intervention in AML

A

> 4 cm

  • Sx
  • female of child bearing age
23
Q

epi of RCC

A

85% of renal CA

  • M>F
  • later in life
  • few risk factors except smoking
  • 95% sporadic
24
Q

RCC presentation

A
  • most are incidental findings
  • common mets
  • paraneoplastic sydrome common
25
Q

terrible triad for RCC

A
  1. flank pain
  2. flank bulge
  3. hematuria
26
Q

5 types of RCC, sites and genes

A
  1. clear cell - 70%
    - PCT
    - VHL gene
  2. papillary - 10%
    - PCT
    - type 1 and 2
  3. chromophobe
    - CD
    - less aggressive
  4. collecting ducts
    - CD
    - more aggressive
  5. other
27
Q

what is staging and what is it based on

A

TNM

CT and final T stage based on patho

28
Q

what is main imaging for RCC

A

US

- more are incidentally found on CT

29
Q

features of RCC on US

A
  1. variable appearance
  2. solid mass
    - hypo, iso, or hyper echoic
    - calcification
    - doppler vascularity
    - narrow rim
    - renal vein thrombosis
30
Q

4 features of RCC on CT

A
  1. multiphase aquisition
  2. enhancing mass
    - increased desnity after contrast
  3. calcifications
  4. staging
31
Q

when to use MRI

A
  • contraindication to CT
  • confirm equivocal CT
  • characterize CT enhancement
  • RCC subtyping
32
Q

3 RCC mimics on imaging

A
  1. dromedary hump - normal variant
  2. coloumn of bertin
  3. renal abscess
33
Q

*when to use a biopsy (3)

A
  1. if unsure of Dx
  2. if it might alter mgmt
  3. if have a good GU IR and patho
34
Q

5 prognositic factors for RCC

A
  1. stage - most important
  2. grade
  3. tumor size
  4. histo variant
  5. patient age/health
35
Q

main Tx

A

surgery

- chemo and RAD resistant

36
Q

2 main surg

A
  1. radial nephrectomy
    - gold standard for advances
  2. partial
    - preferred when feasible
37
Q

2 other Tx options

A
  1. thermal ablation

2. active surveillance