blood transfusions

Question 1

3 parts in blood

Answer 1

1. plasma
2. buffy coat
3. RBCs

Question 2

what is alternative to RBCs for anemia

Answer 2

Fe

Question 3

what’s in a unit of RBC

Answer 3

160ml RBC
1-20 plasma
100ml anticoag

Question 4

how much does 1 unit raise Hb

Answer 4

10g/L

Question 5

3 levels of Hb and what to give

Answer 5

> 90 - no

70-90 - depends on PT factors

Question 6

what is recommendation of symptomatic CAD

Answer 6

> 90 - no

70-90 - depends on PT factors - even in CAD and elderly, closer to 80

Question 7

how to transfuse RBCs

Answer 7

1 unit at a time over 2 hours and not more than 4 hours

• consider slower with furosemide if imparied cardiac funct
• assess outcome befoer more

Question 8

2 times to be cautious about platelet transfusions

Answer 8

1. trombotic thromobocytopenic dis.
   - TTP
   - HIT
   - ALPA
2. immune thrombocytopenia
   - prednisone more effective

Question 9

manifestations of thrombopenia

Answer 9

1. proimary hemo stasis issues

2. bleeds

Question 10

what in dose of platlets

Answer 10

1 boffy coat of plts from 4 donors

= 250-300 ml

Question 11

how much does one unit of plts raise

Answer 11

count by 15-20

Question 12

when to tranfuse platelets (4 levels)

Answer 12

under 10 - prevent spont. bleeds

Question 13

how to tansfuse plts

Answer 13

1 dose over 1-2 hours max 4

Question 14

what happens in low clotting factors

Answer 14

bleeds - high IRN

- require levels at 30-50%

Question 15

whats in a unit of flozen plasma

Answer 15

250ml
all necc. clotting factors
1/2 life 6-8 hours

Question 16

how much for a dose

Answer 16

brings up factors by 20%

Question 17

2 times to give plasma

Answer 17

1. major bleed or procedure and INR>1.5

2. microvasc bleeds and cannot wait for labs

Question 18

3 practical tips for frozen plasma

Answer 18

must be thawed

• must be ABO compatible
• universal is AB plasma

Question 19

what are prothrombin complex concentrates

Answer 19

Vi K factors - 10,9,7,2, C,S
pooled
for urgent or emergent reversal of warfarin

Question 20

how to give PCC

Answer 20

1000 units over 15 minutes

- need to give vit K for prolonged reversal

Question 21

what are probs. with low fibrinogen

Answer 21

• microvasc bleed

- complicate massive hemmorhage

Question 22

what is in unit of cryoprecipitate

Answer 22

15mls

- fibrinogen and factor 8, 13, VWF

Question 23

what does does (10 units) raise by

Answer 23

0.5g/l

Question 24

2 levels to give cryoprecipitate

Answer 24

fibro