Shreiber ABs Flashcards

1
Q

7 bugs in resp. cluster

A
  1. pneumococcus
  2. H. influenzae
  3. Moraxella catarrhalis
  4. meningococcus
  5. chlamydophylae pneumoniae
  6. mycoplasma pneumonaie
  7. Group A strep
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2
Q

5 resp. syndromes

A
  1. otitis media
  2. sinusitis
  3. pharynigitis
  4. pneumonia
  5. meningitis
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3
Q

3 bugs in intra-abdo cluster

A
  1. Gr- bacilli
  2. anaerobes
  3. enterococci
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4
Q

6 abdo syndromes

A
  1. diverticoutis
  2. intra-abdo abscess
  3. cholecyctitis
  4. pyelonephritis
  5. PID
  6. diabetic foot infection
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5
Q

2 bugs in skin

A
  1. Group A strep

2. S. aureus

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6
Q

3 syndromes in skin

A
  1. cellulitis
  2. erysipelas
  3. abscess
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7
Q

what are 3 big AM families

A
  1. penicillins
  2. cephalosporins
  3. FQs
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8
Q

4 “pretty big” families

A
outpatients
1. macrolides
2. tetracyclines
inpatients
1. carbapenems
2. aminoglycosides
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9
Q

5 individuals

A
  1. vancomycin
  2. trimethoprim-sulfa
  3. nitrofuenatoin
  4. metronidazole
  5. clindamycin
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10
Q

bugs for penicillin

A

strep, pneumococcus, treponium pallidium

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11
Q

bugs for ampi/amoicillin

A

amino group

-strep, pneumococcus, treponium pallidium + some Gr-

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12
Q

what are 2 add-ons for penicillins

A

clavulanate or tazo - give broader spectrum

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13
Q

coverage for cloxacillin

A

same as penicillin, but with S. Aureus

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14
Q

2 important groups of cephalosporins and names

A

1st gen - cephalexin and cefazolin

3rd gen - cefixime, ceftriaxone, cefrazidime

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15
Q

what do 2 generations cover

A

1st - Gr+

3rd - Gr-

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16
Q

2 keys FQs and their coverage

A
  1. ciprofloxacin - aerobic Gr- rods

2. respiratory FQs (levofloxacin, moxifloxacin) - aerobic Gr- rods, bacteria causing pneumonia, aerobic Gr- cocci

17
Q

coverage by macrolides

A

Gr+ cocci, bacteria causing pneumonia, some Gr- including those causing gon and traveller diarrhea

18
Q

coverage by tertacyclines

A

pneumonia bacteria, chlamydia, broad spectrum including MRSA

19
Q

coverage by aminoclycocides

A

aerobic Gr-

20
Q

coverage by carbapenems

A

everything but MRSA

21
Q

coverage by trimethoprim-sulfa

A

broad spectrum, esp Gr- , MRSA

22
Q

coverage by nitrofurantoin

A

Gr- bacillis, enterococcus (BOTH only for CYSTITIS)

23
Q

coverage by metronidazole

A

anaerobes, C.diff

24
Q

coverage by clindamycin

A

Gr+ cocci (yes MRSA, no enterococci), anaerobes

25
Q

coverage by vancomycin

A

aerobic Gr+ cocci

26
Q

1st and 2nd choice for Strep A

A
  1. penicillin

2. 1st gen cephalosporin, macrolide, resp. FQ

27
Q

1st and 2nd choice for Strep pneumoniae

A
  1. penicillin

2. 2 or 3 gen cephal, macrolide, resp FQ, vanco

28
Q

1st and 2nd choice for entercoccus

A
  1. amoxicillin

2. vanco, linolizid

29
Q

1st and 2nd choice for s. aureus (non-MRSA)

A
  1. cloxacillin

2. 1st gen. cephalo, vanco

30
Q

1st and 2nd choice for MRSA

A
  1. blood - vanco, skin- clindamycin
31
Q

Choices for typical enteric pathos (E.coli, proteus, klebsiella)

A
  1. FQ
  2. 3rd gen cephalo
  3. amoxicillin-clav
32
Q

choices for H. influenzae, moraxella

A
  1. amoxicillan
  2. cephalo - 3rd gen
  3. resp FQ
33
Q

choices for neisseria meningitidis and gonorrhea

A
  1. 3rd gen cephalo (ceftriaxone)

2. add azithromycin or doxicylin for gon

34
Q

drugs for chlamydia trachomatis and mycoplasma pneumoniae

A
  1. azithromycin

2. doxicycline

35
Q

drugs for bacteroides and other oral and gut anaerobes

A

metronidazole

36
Q

drugs for C.diff

A

metronidazole

37
Q

8 issues to think about when choosing the meds

A
  1. local resistance patterns
  2. recent AB use
  3. co-morbidities that may alter
  4. if the patient is very sick
  5. cost
  6. safety issues
  7. tissue penetration
  8. cidal vs .static
  9. evidence from randomized trials
38
Q

what to do when culture is returned

A

narrow the spectrum

39
Q

go through the samples

A

now