LEcture 4 - cohort

Question 1

basic steps

Answer 1

1. start with inception cohort
2. assess particpant exposure at baseline and divide into groups based on exposure status
3. can be prospective or retrospective

Question 2

strengths

Answer 2

1. use when RCTs not feasable
2. best design when assessing harms of something (can’t RCT)
3. can assess prognosis
4. strong for assessing causation (temporal)
5. good flexibility, precision, anc control for assessing exposres
6. can collect on multiple outcomes
7. limits recall bias

Question 3

weaknesses

Answer 3

• expensive
• time consuming
• groups not randomly generated
• confounds

Question 4

2 ways to deal with confounds

Answer 4

1. design (matching)

2. analysis (stratification)