body fluid compartments Flashcards

1
Q

what is osmosis

A

diffusion of water form high to low solutes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is osmolarity

A

[C} of all particle mosm/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is normal body osmolatiry

A

295 mosm/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are 2 types of pressure that can move fluids

A
  1. hydrostatic - push

2. osmosis - pulls (sucking)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is total body water in men and women

A

men - 60%

women - 50%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

how much water in most tissue

A

75-80%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

where is total body water

A

ECF - 1/3

ICF - 2/3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

where is most ECF water

A

interstitial 3/4 (25% total)

plasma 1/4 (8% total)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is composition of plasma

A

93% water, 7% solids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is sequestered water

A

unavailable water in the bone and CT - not counted for calclulations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what factors affect water

A

age - less with age
women - less water
fat - less with fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is average blood volume

A

70cc/kg – 5L in normal male - 3L plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is border between ICF and other

A

cell membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is border between plasma and ISF

A

cap walls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how does water get into cells

A

through aquaporin channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what happens when add salt to body

A

water exits cells

17
Q

what is tonicity

A

[C] off effective osmoles (usually Na)

18
Q

what is hypertonic

A

more solute than normal

19
Q

what are main ECF and ICF cations

A

ECF - Na

ICF - K

20
Q

what maintains differences between Na and K

A

ATP ase - NA out and K in

21
Q

what is normal ECF [Na}

22
Q

what percentage of osmolarity is Na

23
Q

what is size of ICF and ECF compartments dep on?

A

water - follows the solutes, but solutes don’t pass easily

24
Q

what is osmolarity forumula

A

particles/vol

25
what us ICF volume formula
ICF vol = # ICF particles/ECF osmolarity -- ICF volume is inversely proportional to ECF osmolarity
26
what happens if add 3L of water to ECF
2L to ICF and 1L stays in ECF
27
what happens to ICF in hyponatremia
ICF up - swollen
28
what happens to ICF in hypernatremia
ICF down - shrunken
29
what are 2 exception to hyponatreemia rules
1. hyperglycemia - water leaves cells and shrink, yet hyponatremia 2. hypertriglyceridemia
30
what does [Na} tell you about ECF volume
nothing!
31
what can diffuse through a small cap
only water and small solutes
32
what is main diff between plasma and ISF consitiuents
plasma has high protein concentrations, solute levels are about the same
33
what are 2 ways solute move across the membrane
1. diffusion | 2. solvent drag
34
what happens to ECF volume if we add Na
volume rises
35
what happens to ICF if add isotonic fluid
no change - ECF will go up though
36
physical exam signs of increased ECF
1. edema 2. JVP 3. rapid weight gain 4. maybe hypertension
37
physical exam signs of low ECF
1. dry mouth/eyes 2. poor skin turgor 3. low blood volume signs