optic nerve: anatomy and disorders Flashcards

1
Q

most common site of traumatic optic neuropathies

A

blow to the brow - attached to the dura in the optic canal

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2
Q

what do ganglion cells respect in the retina

A

the horizontal midline

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3
Q

what percentage of gnaglion cells duccusate

A

53% cross

47% remain on same side

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4
Q

where is common site of optic nerve constriction

A

lamina cibrosa

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5
Q

what is special about the cup in the disc

A

devoid of any axons and tissue (white)

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6
Q

what is normal cup to disc ratio

A

0.3

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7
Q

what is large cup a sign of

A

glaucoma

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8
Q

5 ways to test optic nerve function

A
  1. central visual acuity
  2. RAPD
  3. visual fields
  4. color testing
  5. contrast sensitivity
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9
Q

what is an RAPD a sign of

A

optic nerve damage in that eye - most optic neuropathies are assymetric and thus will have an RAPD

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10
Q

3 keys things to assess in the optic nerve clincally

A

Borders - are they sharp?
Color - pink is normal - is there pallor
Cup - can I see it - ratios

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11
Q

what is papilledema

A

swelling of the optic nerve head due to increased ICP - usually bilateral

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12
Q

pathophysio of pappiledema

A

increase ICP>less space for CSF>CSF excess around optic nevre> swelling

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13
Q

when might pappiledema be assymetric

A

if the nerve is atrophic

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14
Q

what is axoplasmic stasis

A

increase ICP transmitted to optic nerve along meningeal sheaths - stops axoplasmic flow at lamina cibrosa

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15
Q

what is diff b/w papill and other optic neuropathies

A

in pap the visual acuity is pretty normal

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16
Q

tests for pappiledma

A

imaging and if normal > lumbar puncture to meausre pressure and CSF

17
Q

5 other types of optic neuropathies

A
  1. congenital
  2. inflammatory
  3. ischemic
  4. toxic metabolic
  5. traumatic
18
Q

2 cats of inflammatory

A
  1. infectious - TB, syphillis, virus

2. non-infectious - idopathic, sacroid, Wegners

19
Q

what is most common optic neuropathies in under/over 50

A

under - demylenating

over - ischemic

20
Q

2 types of ischemic

A

arteritic - rarer, but more devastating

non-arteritic - treatable

21
Q

Sx of demylenating (3)

A
  1. unilateral vision loss
  2. RAPD
  3. pain on eye movements
22
Q

what is relat between optic neuritis and MS

A

50% will dev. MS - even one lesion is predictive - better MS outcomes though

23
Q

what is non ateritic ischemia

A

wake up with vision loss and is often altitidunal - hypoperfusion

24
Q

what is giant cell arterititis

A

inflammation of wall of medium size vessels - occludes lumen

25
Sx of GCA
1. jaw cluadication 2. scalp tenderness 3. headache weight loss chills
26
markers of GCA
ESR and CRP
27
treatment of GCA
high dose steroids to save vision