General cancer therapy Flashcards
**6 key features when taking an HPI for onc
- Sx and important risk factors
- diagnosis (path report)
- stage
- treatment until now
- peformace status
- PT understanding of illness
** how is diagnosis made
biopsy
3 types of biopsy
- fine needle
- core biopsy
- excisional
3 features of staging
T,N,M
what is staging used for
progonsis and treatment
general rules to staging
1and 2 early
- locally advanced
- mets
what is ECOG measure
performance status - higher is worse
***4 treatment modalities and the extent they can reach
- surgery - local
- radiation - local
- drug - systemic
- interventional
4 general types of drug treatments
- chemo
- hormonal
- targeted
- interventional
what does treatment depend on
- path
- stage
- other factors (age, PGOG)
***4 possible goals of chemo
- cure
- cure along with RT
- adjunctive
- palliative
2 types of adjunctive therapy
- neo adjuvant - before surgery
2. adjuvant - after surgery
how does treatment duraiton change between curative, adjuvant, and palliative
curative and adj - limited
palliative -as long as good response
** 3 main SE of chemo
- bone marrow
- GI
- hair, fatigue
3 bone marrow probs
- anemia
- neutropenia
- thrombocytopenia
3 GI issues
- mucositis
- nausea/vomiting
- diarrhea
*** what is targeted therapy
interference with specific molecules involved in CA growth
2 examples of targeted therapies
- tyrosine kinase inhibitors (-nib) - slow growth
2. monoclonal ABs (-mab) - bind receptors
what happens if cancer comes back
not usually curable at that point - palliative
