General cancer therapy Flashcards

1
Q

**6 key features when taking an HPI for onc

A
  1. Sx and important risk factors
  2. diagnosis (path report)
  3. stage
  4. treatment until now
  5. peformace status
  6. PT understanding of illness
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2
Q

** how is diagnosis made

A

biopsy

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3
Q

3 types of biopsy

A
  1. fine needle
  2. core biopsy
  3. excisional
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4
Q

3 features of staging

A

T,N,M

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5
Q

what is staging used for

A

progonsis and treatment

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6
Q

general rules to staging

A

1and 2 early

  1. locally advanced
  2. mets
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7
Q

what is ECOG measure

A

performance status - higher is worse

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8
Q

***4 treatment modalities and the extent they can reach

A
  1. surgery - local
  2. radiation - local
  3. drug - systemic
  4. interventional
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9
Q

4 general types of drug treatments

A
  1. chemo
  2. hormonal
  3. targeted
  4. interventional
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10
Q

what does treatment depend on

A
  1. path
  2. stage
  3. other factors (age, PGOG)
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11
Q

***4 possible goals of chemo

A
  1. cure
  2. cure along with RT
  3. adjunctive
  4. palliative
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12
Q

2 types of adjunctive therapy

A
  1. neo adjuvant - before surgery

2. adjuvant - after surgery

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13
Q

how does treatment duraiton change between curative, adjuvant, and palliative

A

curative and adj - limited

palliative -as long as good response

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14
Q

** 3 main SE of chemo

A
  1. bone marrow
  2. GI
  3. hair, fatigue
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15
Q

3 bone marrow probs

A
  1. anemia
  2. neutropenia
  3. thrombocytopenia
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16
Q

3 GI issues

A
  1. mucositis
  2. nausea/vomiting
  3. diarrhea
17
Q

*** what is targeted therapy

A

interference with specific molecules involved in CA growth

18
Q

2 examples of targeted therapies

A
  1. tyrosine kinase inhibitors (-nib) - slow growth

2. monoclonal ABs (-mab) - bind receptors

19
Q

what happens if cancer comes back

A

not usually curable at that point - palliative