intro to immune system

Question 1

3 ways skin protects

Answer 1

1. barrier
2. immune cells that initiate immune respone
3. produces antibacterial moelcules

Question 2

where do key immune cells come from

Answer 2

bone marrow

Question 3

2 primary lymphoid organs

Answer 3

1. thymus - matures T cells

2. marrow - makes B cells

Question 4

secondary lymphoid tissues

Answer 4

all other - spleen, tonsils, lymphnodes

Question 5

where are 2 types of cells in the lymph node

Answer 5

1. cortical area - B cells undergo clonal expansion

2. paracortical area - mostly T cells

Question 6

where do most infections occur in humans

Answer 6

in mucosal tissues

Question 7

what is protection around the mucous membranes

Answer 7

peyer patches and tonsil/adenoids

Question 8

function of neutrophil

Answer 8

phag and activates bacteria-cide

Question 9

funct. eosonophil

Answer 9

killing of antibody coated parasites

Question 10

funct. of basophil

Answer 10

unknown

Question 11

funct. of mast cell

Answer 11

release granules of hist and allergy

Question 12

3 major classes of lymphocytes and fucntion

Answer 12

t cell - cellular immune repsonse
B cell - become plasma cells and make antibodies
NK cell - kill virally infected and cancer cells

Question 13

what is unique about T and B cells

Answer 13

unique to a specific antigen

Question 14

how are infectious agents first recognized

Answer 14

toll like receptors on macrophages

Question 15

funct. of dendritic cell

Answer 15

uptakes antigens in periphery and present to T cells

Question 16

what does a stimulate T cell do

Answer 16

actiavtes B cell along with the antigen

Question 17

what does activated B cell do

Answer 17

prolifeates and makes antibodies

Question 18

3 ways antibodies eliminate stuff

Answer 18

1. neutralizes toxins by binding
2. opsinization of bacteria for phaging
3. complement binding of bacteria

Question 19

what is required for successful presentaiton to T-cell

Answer 19

MHC

Question 20

what does helper T-cell do (2)

Answer 20

1. recognizes complex of bacterial peptdes with MHC II and activates macrophage
2. recognizes complex of antigenic peptides with MHC II and activate B cell