pancreatic CA Flashcards
1
Q
main type of pancreatic
A
adenocarcinoma
- also cystic, endocrine and other
2
Q
epi
A
- 4th leading cause of CA death
- rare before 45
- male>female
- african higher
3
Q
risk factors
A
- heredity - 5-10%
- smoke
- obese
- chronic pancreatitits
- diabetes
4
Q
2 main types of gland to become
A
1- exocrine
2. endocrine
5
Q
tumor staging (3)
A
- size
- extent of local invasion
- involvment of SMA (automatically T4 and hard to resect)
6
Q
what is stage based on
A
size and degree of adjacent involvment
7
Q
what is common pattern
A
perineural spread
8
Q
clinical features
A
head - jaundice
tail - silent until advanced
9
Q
how to diagnose
A
imaging: CT/MRI + endo US
markers: CA 19
Path: only if other tests not diagnosis - FNA
10
Q
treatment
A
early: surgery - whipples, or pancreatectomy
advanced: chemo
11
Q
prornosis
A
very bad, even if early
