Peirpheral neuropathy Flashcards
what is peripheral nervous system
- originates and ends in the spinal cord
- motor and sense system involved in invountary reflex arc and voluntary control/awareness
7 possible localizations in peripheral system
- myopathy
- NMJ
- mononeuropathy
- plexopathy
- radiculopathy
- motor/sensory neuropathy
- polyneuropathy
3 principles of nerve conduction
- propagation is analagous to transmission in CNS
- depol. hyperpol. dependednt on Na/K
- strength and speed depend on type of nerve fiber
what is saltatory conduction
myelin covering means you can jump
- autonomic is much slower due to lack of myelin
4 mechs of nerve injury
- disrupted axonal transport (most common)
- nerve infarct
- nerve inflammation
- compression/direct injury
what are 2 types of axonal transport and what do they transport?
- anterograde - essential nutrients to the nerve
2. retrograde - returns debris to cell body for recycling
what nerves oare most likely to be disrupted
longest (toes) and thickest (sensory)
what is polyneuropathy
most common
- lenght dependent due to disruption in axonal transport
5 sensory Sx of polyneropathy
- itch
- burning
- freezing
- tingling
- numbness
3 motor Sx of polyneuropathy
- cramps
- weakness
- gait diff./falls
7 autonominc features of polyneuropathy
- syncope
- arrythmia
- incr./decr. perspirtation
- diarrhea/constipation
- bladder dysfunciton
- visual blurring
- sexual dys
6 general causes of symetrical distal polyneuropathy
- metabolic - endo, organ dysfunction
- nutritional
- toxic - env and meds
- infection
- CA
- CT diseases
most common cause
diabetes
- in world used to be leprosy
what does EMG tell us
- if and where there is dysfunction
- extent of injury
- duration
- type of damage
NOT - etiology
- central involvement
what is nerve conduction
evaluates sense and motor nerves in the limbs
