EXAM Qs

Question 1

Thyroid hormone effects (9)

Answer 1

1. Na/K ATP ase - Na out/ K in
2. increased O2
3. heat gen, sweating
4. incr. glycolysis
5. incr. lipolysis
6. weight loss
7. B - andronergic effects - resp and CV up
8. increased metabolism

Question 2

what inhibs TSH (4)

Answer 2

1. dopamine,
2. somatostatin
3. glucocorticoids
4. TH

Question 3

what are 4 main effects of GH release

Answer 3

1. bone growth
2. protein syntesis
3. hyperglycemia
4. lipolysis

Question 4

4 metabolic effects of glucocorticoids

Answer 4

1. up hepatic glucogenisis - conversion of AA to glucose
2. up protein catabolism - more AA in blood
3. down glucose tissue uptake - more glucose for brain
4. up lipolysis - alternative E source

Question 5

permissive effect of GCs

Answer 5

increase catecholamines - more CV response in stress

Question 6

In met acid. what does too high or low pCO2 compensation tell us

Answer 6

too high - resp acid

too low - resp alk

Question 7

normal anion gap

Answer 7

12

Question 8

normal osmolar gap

Answer 8

10 - alcohol (ethylene glycol or methanol)

Question 9

creatinine clearance formula

Answer 9

amount excreeted/[Creatinine]plasma

Question 10

site of action and mech of 5 diuretics

Answer 10

acetazolamide - PCT - Carbonic anhydrase inhib
furiosemide -thick ascending - NaK2Cl inhib
hydroclorothiazide/metazone- DCT - NaCl inhib
sprironolactone - CCD - aldo antag
amiloride.triamtrene - CCD - Na channel blocker