vasoregulation -bolz Flashcards

1
Q

what is most problematic metabolic biproduct

A

CO2

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2
Q

where is high P system, and how much blood there

A

arteries - 23%

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3
Q

how does blood dist change in excercise

A

major increase to muscle, away from gut

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4
Q

3 important functions of RBC being too large for caps

A
  1. slows time
  2. increases surface contact
  3. little distance to walls
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5
Q

what is importance of small and medium arteries

A

bring P down before caps.

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6
Q

how do resistance arts. reg. P to caps.

A

constrict r to change resitance

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7
Q

what are adrenaline targets, where do they occur, and what do they do (2)

A

a-receptors - gut - vasoconstrict

B-receptors - muscle - dilate

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8
Q

what is step 1 of mygenic response

A

muscles signal need for more blood - dilates sector 1

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9
Q

what art. reaction to increase in P (2 steps)

A
  1. immediate swelling

2. hard contraction against P

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10
Q

what does adrenaline do to BP on its own

A

incr. BP

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11
Q

what do resistance arts. do in response to high BP

A

constrict to protect Caps.

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12
Q

what is main regulator of tone in resistance As

A

myogenic response

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13
Q

within what BP range will blood flow to brain be constant

A

60-170

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14
Q

what is sector 2s response to metabolic activity

A

descrease perfusion pressure

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15
Q

whats is sector 3’s response to sector 2

A

increase blood flow

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16
Q

what are 3 types of vasodilation in 3 sectors

A
  1. metabolic
  2. myogenic
  3. endothelium mediated
17
Q

what is competing model to myogenic response

A

conducted vasodilation vis connexons

18
Q

how can we assess connexon model

A

Cx40 (connexon gene) knockout lead to reduced conduction