Resp control and sleep Flashcards

1
Q

path of a feedback loop

A

contoller>output>effector>feedback>sensor>input>controller

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2
Q

what happens in pos feedback loop

A

controller will further augment the effector > runaway behavior

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3
Q

what happens in neg. feedback loop

A

controller will reduce the effector > stabilizes and promotes equilibrium

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4
Q

what is receptor, controller and effector of resp

A

receptor - sensors
controller - brain
effector - muscles

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5
Q

what are 3 areas of medulla and what do they control

A
  1. ventral - expiration
  2. dorsal - inspiration
  3. botzinger area - pacemaker
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6
Q

2 areas of pons and what they do

A
  1. apneutic area - exitatory - stims dorsal medulla

2. pneumotaxic area - regulates length of breath

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7
Q

what does the cortex do?

A

give and override system

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8
Q

what does limbic system do?

A

involved in emotional response

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9
Q

what are the 2 main classes of receptors

A
  1. chemoreceptors

2. lung receptors

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10
Q

2 locations of chemoreceptors

A
  1. central - medulla

2. peripheral

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11
Q

2 locations of peripheral chemorec

A
  1. aorta

2. carotid body

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12
Q

3 types of lung receptors

A
  1. stretch
  2. irritant
  3. J
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13
Q

what do central chemoreceptors detect and how

A

pCO2 through H+ passing blood brain barrier

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14
Q

what do carotid chemoreceptors respond to and how (3)

A
  1. PaO2 - if low more vent
  2. PaCO2 - if high more vent
  3. pH - if low more vent
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15
Q

what do aortic chemoreceptors respond to

A

paO2 and paCO2

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16
Q

what are peri chemoreceptors more responsive to

A

changes in paO2

17
Q

at what point do paO2 receptors really start to fire

A

below 50mmHg

18
Q

what do stretch receptors do

A

stim by lung inflation and lead to incr. expiratory times

19
Q

what do irritant receptors respond and what do they do

A

inhaled irritants - bronchcontrict and incr. vent.

20
Q

what do J receptors do

A

stim by engorged capils. and lead to rapid shallow breathing

21
Q

what are central chemorepetors most responsive to?

A

pCO2

22
Q

what is most important driver of resp.

A

pCO2

23
Q

what do narcotics do

A

reduce response to pCO2

24
Q

how does pCO2 change the pO2/vent curve

A

brings it up

25
Q

what happens to patients with chronic COPD if give O2

A

chronic COPD causes decrease pCO2 sensitivity and pO2 becomes more important driver of vent. > if give O2 will drop their vent rates

26
Q

what is Kussmaaul’s breathing

A

ketoacidosis - leads to deep breathing because body is trying to blow off acid via CO2

27
Q

what is breathing pattern in stage 1 sleep

A

unstable variations between hypo and hyper ventilation

28
Q

breathing in stage 2-4?

A
  • regular breathing
  • blunted response to hypercapnea and hypoxia
  • hypoventialtion
  • higher pCO2 and lower pO2
  • higher upper airway resistance
29
Q

breathing in REM sleep?

A
  • erratic shallow breathing
  • higher blunting of hypoxia and hypercapnea
  • more hypoventilation
  • airway resistance is highest
30
Q

why does sleep apnea occur

A

reduced upper airway dilator muscle activity - collapses>hypoxia>wake up

31
Q

what is cheyne-strokes respiration

A

cescendo/decrcendo breathing with period of apnea