Resp control and sleep Flashcards
path of a feedback loop
contoller>output>effector>feedback>sensor>input>controller
what happens in pos feedback loop
controller will further augment the effector > runaway behavior
what happens in neg. feedback loop
controller will reduce the effector > stabilizes and promotes equilibrium
what is receptor, controller and effector of resp
receptor - sensors
controller - brain
effector - muscles
what are 3 areas of medulla and what do they control
- ventral - expiration
- dorsal - inspiration
- botzinger area - pacemaker
2 areas of pons and what they do
- apneutic area - exitatory - stims dorsal medulla
2. pneumotaxic area - regulates length of breath
what does the cortex do?
give and override system
what does limbic system do?
involved in emotional response
what are the 2 main classes of receptors
- chemoreceptors
2. lung receptors
2 locations of chemoreceptors
- central - medulla
2. peripheral
2 locations of peripheral chemorec
- aorta
2. carotid body
3 types of lung receptors
- stretch
- irritant
- J
what do central chemoreceptors detect and how
pCO2 through H+ passing blood brain barrier
what do carotid chemoreceptors respond to and how (3)
- PaO2 - if low more vent
- PaCO2 - if high more vent
- pH - if low more vent
what do aortic chemoreceptors respond to
paO2 and paCO2
what are peri chemoreceptors more responsive to
changes in paO2
at what point do paO2 receptors really start to fire
below 50mmHg
what do stretch receptors do
stim by lung inflation and lead to incr. expiratory times
what do irritant receptors respond and what do they do
inhaled irritants - bronchcontrict and incr. vent.
what do J receptors do
stim by engorged capils. and lead to rapid shallow breathing
what are central chemorepetors most responsive to?
pCO2
what is most important driver of resp.
pCO2
what do narcotics do
reduce response to pCO2
how does pCO2 change the pO2/vent curve
brings it up
