Transfusion risk and reactions Flashcards
1
Q
2 main blood infections from 70s and 80s
A
HIV and hepC
2
Q
5 key points to informed consent
A
- obtained by treating phys
- mandatory except emergecy and no decision maker
- benefit, risk, alt. discussed
- documented
- advise patient what was given after
3
Q
what is most common risk
A
transfusion associated circ. overload
4
Q
- 3 things patients worry about
A
HIV, hep B and C
- 1/millions
5
Q
what are most common
A
fever and hives
6
Q
what are most common cause of death
A
TACO - circ overload
2. TRALI - trans assoc. acute lung injury
7
Q
4 Sx occuring during or shortly after
A
- fever
- uritcaria
- dyspnea
- hypotension
8
Q
def. fever and DDx (4)
A
1degree rise and temp over 38
- acute hemolytic transfusion rxn (AHTR)
- bact.
- febrile non-hemolytic trans. rxn
- fever due to underlying illness
9
Q
mech. and manifestation of AHTR
A
mech - incompatibility of donor and recip. manif - fever, chills - hemouria, pain, hypotension, N/V, DIC
10
Q
MGMT of AHTR
A
- stop trans!
- check clerical errors
- notify blod bank
- send samples to recheck PT blood type
- send labs to look for hemolysis
- supportive care
11
Q
potential causes of bact.
A
- normal skin flora
- bacteremia in donor
- contamination in handling
- most often platelets (room temp)
12
Q
Sx of bact
A
- fever, chills
- hemouria, pain, hypotension, N/V, DIC
13
Q
mgmt of bact
A
- stop trans
- notify bank and send back bloods
- culture Pt
- broad spectrum ABs
14
Q
mech of febrile non-hemolytic trans. rxn
A
- cytokines in transfused products
- recipietn ABs in the transfused product
15
Q
manif of febrile non-hemolytic trans. rxn
A
fever
- maybe worse
- diag. of exclusion
