Infectious diseases in the ER Flashcards

1
Q

what is classic triad of bact. meningitis

A
  1. fever
  2. neck stiffness
  3. altered mental status
    (4) headache
    absence of all 3 eliminates diagnosis
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2
Q

what is usual presentation of Bmen

A

2/4 symptoms in 95% of cases

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3
Q

what are signs to looks for (3)

A
  1. papilledema
  2. brudzinski’s sign
  3. kernig’s sign
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4
Q

4 short term complications of Bmen

A
  1. altered mental status
  2. elevated ICP
  3. seizures
  4. focal neuro deficits
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5
Q

4 long term comp. of Bmen

A
  1. cerebrovasc. abnormalities
  2. intellectual impariment
  3. sensorineural hearing loss
  4. death
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6
Q

6 investigations to order for BMen

A
  1. labs - CBC, BUN
  2. ECG
  3. cultures
  4. urinalysis/culture
  5. CT head
  6. lumbar puncture
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7
Q

what to look for on CT head

A

space occupying lesion or elevated ICP

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8
Q

where to do lumbar puncture

A

b/w L3 and L4

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9
Q

what is taken in 4 vials of LP

A
  1. cell count and differential
  2. glucose, protein
  3. Gram stain, culture, special studies
  4. cell count and differential, xanthrochromia
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10
Q

what is abnormal cell count

A

elevated WBCs

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11
Q

what is abnormal glucose

A
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12
Q

what is abnormal protein

A

> 1 g/L

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13
Q

what is seen on gram stain

A

nothing in 60% - esp. if on antibiotics before LP

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14
Q

what is treatment key in BM

A

start if suspected

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15
Q

treatment of BM

A
  1. IV dexamthasone - stop host mediated inflammation

2. ampicillin, vancomycin, ceftriaxone

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16
Q

organisms in BM

A

strep pneumonia, listeria, menigococcus,

17
Q

what is nec. fasc.

A

deep seated infection in the sub-cut tissues - runs in the fascial planes

18
Q

risk factors for NF

A

drug use, DM, obesity, immunosupression

19
Q

3 systemic findings in NF

A
  1. fever
  2. tachycardia
  3. hypotension
20
Q

Sx of NF

A

tense edema, pain, blisters/bullae, crepitus, subcut. gas

21
Q

2 types of NF

A
  1. polymicrobial

2. monomicrobial

22
Q

def. of type 1

A
  1. at least on anaerobe
  2. one or more facultative anaerobe
  3. one of enterobactersiae family
23
Q

what is usual cause of NF 1 above neck

A

oral anaerobes - fusobacteria, anaerobic strep, bacteroides

24
Q

what is fourniers gangrene and what species

A

genital gangrene

  • facultative org. – e.coli, kebsiella
  • and anaerobe
25
Q

what is type 2

A

hemolytical streptocuccal gangrene

- group A strep or other Beta-hemolytic strep

26
Q

what are common NF investigations

A

labs - generally non-specific - high WBC, INR, lactate, creatinin
imaging - may see gas is soft tissues

27
Q

what is seen in blood cultures in NF

A
    • low yield
  1. ~60%
    most reliable samples are those from surgery
28
Q

**most important therapy of NF (3)

A
  1. early surgical debridement!!!
  2. antibiotics
  3. IVIG