Dementia Flashcards

1
Q

def dementia

A

syndrome of progressive deter. of cog. function sufficient to impact on daily life and occupational function

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2
Q

clinical aspects to assess for dimentia (9)

A
  1. attention problems
  2. memory problems
  3. language problems
  4. visuospatial probs (getting lost)
  5. exec. problems (planning)
  6. praxis problems (doing things in order)
  7. personality and behav. probs.
  8. mood
  9. probs. with daily function
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3
Q

what should be taken on hX (3)

A
  1. past medical
  2. meds
  3. assoc. Sx
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4
Q

what is major risk factor

A

CV risk factors

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5
Q

what does cog. testing do

A

confirms the nature of deficits

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6
Q

what vitals are important

A
  1. hypertension

2. orthostatic HT (lewy body dementia)

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7
Q

9 things not to miss

A
  1. treatable causes of dementia
  2. infections
  3. neoplastic
  4. toxic - esp alc/benzos
  5. obs. sleep apnea
  6. psych - esp depression
  7. vascular
  8. autoimmune encephalopathies
  9. epilepsy
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8
Q

3 stages of mem. loss

A
  1. normal
  2. mild cog. impariment (prodrome)
  3. dementia
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9
Q

def of alzhemiers (3)

A
  1. memory impairment
  2. one of aphasia, apraxia, agnosia, exec. function
  3. loss of social or occ. funciton FROM BEFORE
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10
Q

time from early to death

A

9 years

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11
Q

stages of alz and MMSE scores

A
  1. cog. Sx 25-30
  2. loss of funct. indep 20-25
  3. behav. problems 10-20
  4. nursing home placement 0-10
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12
Q

strongest risk for dementia

A

age

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13
Q

protective factors

A
  1. cog, reserve
  2. excercise
  3. healthy diet
  4. leisure
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14
Q

risk factors

A
  1. genes
  2. CVD
  3. HT
  4. Diabetes
  5. cholesterol
  6. obeisity
  7. smoking
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15
Q

2 features on path of dementia

A
  1. plaques of amyloid

2. tangles of Tau

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16
Q

what is amyloid that is formed

A

amyloid Beta sheets

17
Q

what is consequence of neurodegenrative changes

A

less cholinergic transmission

18
Q

imaging finding of AD

A
  1. biparietal reduction

2. medial temp lobe thickness

19
Q

what is CSF biomarker

A

presence of amyloid

20
Q

what is path of cholinergic defecit

A

loss of chol neurons>decrease in avail Ach>impariments

21
Q

treatment

A

anticholinesterase (donepezil, rivastigmine, galantamine)