Hypothyroid Flashcards

1
Q

thyroid axis

A

hypo>TRH>pit>TSH>thyroid>T3+4>target

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2
Q

where does T34 feedback to

A

hypo and pit (-ve)

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3
Q

4 presentations of thyroid issues

A
  1. hypo
  2. hyper
  3. mass effect
  4. associated probs.
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4
Q

see table of patterns

A

do it

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5
Q

pattern of 1ry hypo

A

TSH up, T3-4 down

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6
Q

what to measure for 1ry hypo

A

just TSH

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7
Q

what to look for in fatigue to help show hypothyroid

A

FHx, common, not depressed, sleeping well, can have normal Phx

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8
Q

labs for hypo

A
  1. TSH, B-HCG
  2. CBC, creatinine, AST - renal failure
  3. fasting glucose - DM
  4. FSH - menpause
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9
Q

what to see on labs for hypothyroid

A

high TSH - can comfortably say

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10
Q

3 tests not to order

A
  1. T4
  2. neck US
  3. anti-thyroid ABs
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11
Q

DDx for hypothyroid

A
  1. congntial
  2. hashimotos
  3. iatrogenic - amiodarone, iodine, radiation, ectomy
  4. subacute thyroiditis
  5. hypothalamic disease (2ry)
  6. peripheral resitance (3ry)
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12
Q

2 most common casues

A
  1. hashimotos

2. subacute thyroiditis

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13
Q

hashimotos presentation

A
  1. other autoimmune
  2. small goitre
  3. pos. anti-thyroid ABs
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14
Q

presentation of subacute thyoiditis

A
  1. inflammation of thyroid
  2. throitoxicosis
  3. may be painful or pain less
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15
Q

treatment of subaucte thyroiditis

A
  1. supportive during toxic phase (B-blocker, pain meds)

2. L-thyroxin during hypothyroid

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16
Q

important things to look out for in thyroid drugs

A
  1. common drug error
  2. take on empty stomach with water
  3. no food or drink for hour
  4. no vits. for 3-4 hours
17
Q

2 times to involve endocrinologust in hypo

A
  1. patient request

2. very young female

18
Q

3 groups that should be screened

A
  1. infants
  2. preggers
  3. those at high risk (famhx, Sx, drugs that can cause)
19
Q

why is newborn screening done

A

prevent dev. delay

20
Q

3 times to treat subclincal hypo

A
  1. patients with Sx
  2. pregnant
  3. TSH>10 - CV risk
21
Q

effects of preg. on normal thyoid

A
  1. maternal thyroid incr. production
    - increase TBG binds thyroid
    - mother supplies thyroid for bb for T1
22
Q

how to adjust meds in preggers

A

T1 increase of 30-50%

23
Q

effect of low thryoid on BB

A

low IQ

24
Q

what to tell women that get pregs

A

take extra 2 pills/week when conceive and call you