Coma Flashcards
define coma
state of unresponsiveness in which patient lies with eyes closed and cannot be aroused even with vigorous stim
what is consciousness a combination of and what defines them
arousal - level of consciousness
awareness - content of consciousness
4 levels of arousal
- alert
- obtunded - reduced but easily stimed
- stupor - reduced alert, and hard to arouse
- coma - eyes remain closed
where must a lesion occur to cause coma
either extensive areas of both hemispheres or the ascending arousal system including paramedian upper brainstem BILATTERALY
what is locked-in syndrome
destruction of pontine base - have awareness, vertical eye movements, and blinking, but otherwise totally paralysed
3 general classes of coma etiology
- structural
- metabolic
- intrinsic
2 types of structural brain issues
- compressive lesions - supra and infratentorial
2. destructive lesion - supra and infra
examples of metabolic cause of coma
- glucose
- anorexia
- lytes
- acid-base
- organ dysfunction
2 types of intrinisic cause of coma
- epilepsy
2. infection
what is a false localizing sign
sign shows a lesion on one side, but on another
what happens in uncal herniation
uncus herniates and compresses stem
signs in right uncal herniation
- R 3rd nerve palsy (localize with this)
- depressed consciousness
- left hemiparesis - pressing against stem
OR right hemiparesis (kernohan’) pressing against opp. tentorium
what happens to eyes in right lateral pontine lesion
gaze paralysis - eyes don’t turn when move head left
what happens to eyes in left paramedian pontine lesion
1.5 syndrome - eyes don’t move when move head right and L eye doesn’t adduct when turn head left
what happens to eyes in MLF lesion
neither eye will adduct
2 main eye function of para system
- contricts pupil
2. accomodates
3 main functions of symp. system
- dilate pupils
- raise eyelids
- acitvate sweat glands
what happens to pupils when lesion CN3
dilated and fixed
what happens to pupils when lesion midbrain EWN
midposition, fixed
what happens to pupils when lesion pons and desceding sym tract
pinpoint pupils
key questions in a coma Hx
- onset
- seizure?
- recent trauma
- febrile illness
- premontory signs
- PMHx
- Meds
3 categories of glasgow coma scale
- eye response
- motor response
- verbal reponse