liver failure and transplant

Question 1

2 types of liver failure

Answer 1

chonic - common

acute (fulminant) - uncommon

Question 2

5 signs of decompensation

Answer 2

1. ascites
2. varcieal bleeds
3. HE
4. jandice
5. HCC

Question 3

5 year survival of decomp

Answer 3

50%

Question 4

how is ascites related

Answer 4

longer with cirrohosis -more ascites

ascites related to worse oiutcomes

Question 5

how does survival change with ascites tim

Answer 5

goes down with time

Question 6

5 stepwise steps to mgmt of ascites

Answer 6

1. Na intake
2. diuretics
3. paracentesis
4. TIPS
5. transplant

Question 7

what is another complications assoc with survival

Answer 7

varices

Question 8

def of HE

Answer 8

potentially reversible neuropsych abnormalities seen in pts with severe liver dysfunction

Question 9

5 grades of HE

Answer 9

0 - normal
1 - mild - sleep, impaired writing
2- mod - asterixis, lethargy
3 - severe - sonolence, not oriented, paranoid
4 - coma

Question 10

major liver cause of HE

Answer 10

infection - SBP

Question 11

main treatment of HE

Answer 11

decrease circ. ammonia

Question 12

pronosis with HE

Answer 12

without transplant - 1 year survival of 20-40

Question 13

what is common scale to predict survival and 3 levels

Answer 13

childs-pugh - ABC

Question 14

3 parts of MELD score

Answer 14

bili, INR, creat

Question 15

which is better predictor

Answer 15

MELD score

Question 16

how many transplants are from living donors

Answer 16

25%

Question 17

most common cause for transplant

Answer 17

HCV - but going down

Question 18

what is growing pop for liver transplant

Answer 18

NASH

Question 19

survival rate for transplant

Answer 19

80%

Question 20

def. fulminant liver failure

Answer 20

potentially reversible condition with onset of HE within 8 weeks and no prior liver disease

Question 21

most common cause

Answer 21

acetominophen