Adverse drug reactions Flashcards

1
Q

what is adverse drug event

A

something bad happens while taking the drug

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2
Q

what is adverse drug reaction

A

something bad happens due to the drug

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3
Q

what are type A reactions

A

dose related - too much of the normal reaction of the drug

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4
Q

what is type B reactions

A
  • bizarre and idiosyncratyic

- not dose related- specific to the person

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5
Q

what is potential reaction to carmbemazepine

A

stevens johnson syndrome for people with specific HLA-B15:20

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6
Q

what are 3 issues for risk management in drugs

A
  1. plan before treatment
  2. care during treatment
  3. what to do in adverse event
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7
Q

4 things to be done before treatment

A
  1. informed consent
  2. determine toxicity risk
  3. baseline assessment
  4. communicate risk to PT
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8
Q

what is SAFER MD informed consent

A
Side effects
Alternative treatments
Forfeit of treatment
Expected benefit
Regimen for dosing
Monitoring
Duration of therapy
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9
Q

3 areas of primary prevention focus

A
  1. high risk drug
  2. high risk patient
  3. high risk situation
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10
Q

what are high risk drugs

A
interactions
4 As 
Antibiotics
Anti-inflammatories
Anti-convulsants
Anti- coagulants
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11
Q

what makes PT high risk

A

contraindications
Age
health
genetics

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12
Q

what is a contraindication

A

DO NOT USE

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13
Q

what is warning

A

think and proceed before use

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14
Q

3 things to do during therapy

A
  1. recognize adverse event
  2. consider drug etiology
  3. determine association
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