Arthritis 2 - OA Flashcards
1
Q
epi of OA
A
75% of all arth
- knee most common leadin to dis
- on the rise
2
Q
3 reasons OA on the rise
A
- obesity
- less activity
- incr. age of pop
3
Q
2 general patterns of OA
A
- localized
- hand
- knee
- hip - generalized
- 3+ joints
4
Q
OA on the spine?
A
common
- in facet joint
- degen disc disease in lumbar spine
5
Q
what is OA not
A
- inevitable part of aging
- degenerative disease
6
Q
what is OA
A
progressive disease of synovial joints from failed repairs of damage reulting from stresses on the joint
7
Q
2 general patterns of pathogenesis
A
- abnormal stress on normal physiology
2. normal stress on abnormal physiology
8
Q
what are age related joint diseases
A
- thinning cart
- less responsive to growth factors
- muscle weakness
- slower reaction times
9
Q
what is sex diff
A
F 2x as M
- hormones
- body shape
- genes
- social?
10
Q
what does genes determine
A
50% of hip, hand, general OA
less for knee
11
Q
how does joint load impact
A
normal joint loading is okay, but when becomes abnormal somehow, then get the problems
12
Q
6 factors that neg. affect the joint load
A
- alignment (mal)
- laxity of knee joint
- nerve damage
- joint injury
- joint deformity
- neuromusc. function
13
Q
what is obesity related to
A
knee and hand
- less hip
- stronger relate for women
14
Q
3 possible cont. of obesity
A
- malalignment
- overloading
- cytokines
15
Q
3 ways to make a diagnosis of OA
A
- imaging
- Sx
- exam
