Insulin resistance + metabolic syndrom

Question 1

5 definitions of metabolic syndrom

Answer 1

1. waist > 102men and 88 women
2. TG > 1.7
3. HDL < 1 men and 1.3 women
4. BP > 135/85
5. glucose >6.9

Question 2

differences for men and women in metabolic (2)

Answer 2

waist and HDL

Question 3

5 additional features of metabolic

Answer 3

1. high uric acid
2. high PAI-1 (clotting)
3. high IGF-1 and low binding proteins
4. low adiponectin
5. high CRP (inflammation)

Question 4

2 main types of problematic ectopic fat

Answer 4

1. liver- steatohepatitis

2. muscle - intramyocellular

Question 5

what happens to metabolic folk in stress

Answer 5

more sensitive - leads to high cortisol and insulin resistance

Question 6

2 consequences of high calories

Answer 6

1. high insulin

2. high IGF-1

Question 7

2 consequences of high insuling resitance

Answer 7

1. high BMI

2. less excercise

Question 8

3 cancers related to high BMI and low excercise

Answer 8

1. colon
2. breast
3. prostate

Question 9

4 steps to liver pathology and their markers

Answer 9

1. normal liver (high insulin, high hlucose, high TG)
2. non-acl fatty liver (high ALT, maybe AST)
3. Non- alc steatohepatitis (high ALT and AST)
4. cirrosis

Question 10

2 consequences of renal disease

Answer 10

1. high BP

2. high inflammation

Question 11

what is added insult to renal disease in diabetes

Answer 11

high glucose

Question 12

4 steps that make connection between insulin and BP

Answer 12

high insulin>Na reabasorbtion> H2O follows>high BP

Question 13

3 other mechanisms that link insulin and BP

Answer 13

1. SNS activity
2. RAAS activation
3. oxidative stress

Question 14

4 behavioral treatments of metabolic

Answer 14

1. less calories
2. more excercise
3. lower GI foods (beans, monounsat fat)
4. a little alcohol