stable coronary art. disease Flashcards
what is diff between stable and unstable CAD
stable
- athersclerosis where blood can still pass
unstable
- athero, but a thrombus has formed - occlusion
biggest risk factor
age
7 major risk factors for CAD
- age
- gender
- smoking
- HT
- dyslipidemia
- diabetes
- fam. Hx
what is relationship to smkoing
quantity relevant
- risk reduction in 3 years
what is Fam Hx importance
polygenic
- most important in younger patients
what is angina
symptom due to myocardial ischemia from myocardial O2 demand that is not being met
4 possible DDx of chest pain
- MSK
- GI
- pulm and mediastinal
- psych
what is Sx of angina
not really pain
- pressure/tightness
- can radiate to arm and neck
3 things NOT char of angina
- location
- only in middle lower abdo
- localized to a fingertip - character
- reproduced by movement or palpation
- pleuritic - duration
- few seconds or for many hours
5 precipitantas
- excercise
- emotion
- eating
- cold
- sex
4 levels of chest pain by activity
- normal
- > 2 level blocks of > 1 flight
3.
def. of typical, atypical and noncardiac angina
Typical - all three 1. substernal chest dscomfort 2. provoked by exertion or emotion 3. releived by rest or nitro Atypical 2/3 Non-caridac 1 or less
who are the best people to give further testing to
those in the intermediate risk in PRE-test prob
2 main types of diagnostic testing and their subtypes
- funtional
- exercise
- nuclear
- stress ECHO - structural
- coronary angiogram
- CT coronary angio
2 main components of all functional testing
- stress
2. test
3 ways we can stress
- excercise
- vasodilators
- persatine
- adenosine - pharma
- dobutamine
what what amount of stenosis is there Sx
excercise - 70%
rest - 90%
what is progression in terms of Sx
- blood flow changes
- wall motion abnormal
- ECG changes
- Pain - Sx - not till late
what is excercise testing
65% accurate
- treadmill and ECG
what is nuclear testing
85% accurate
- give radio tracer
- look at wall take up during rest and activity with SPECT tracer
2 types of defect that can be seen in nuclear and what they mean
- reversible - ischemia
2. fixed - infarct
what is ECHO
90% accurate
- normal heart thickens when contracted by 50%
- look for this wall motion abnormalitiy
what is gold standard
coronary angiography
- invasive
- 1/1000 risk of seriosu complication
look at pre-test prob. stuff
do it
4 non-pharma mgmt of CAD
- excercise
- weight loss
- med. diet
- smoking cess
4 meds
1. antiplatelelt - ASA Anti anginal 2. B-blockers 3. nitrates 4. CCBs
3 interventions for CAD
- percutaneous coronoary interventipon
- stent - drug eluting
- CABG - major