IV fluids Flashcards
where is body water
1/3 ECF
2/3 ICF
where is water in ECF
1/4 plasma (8% total)
3/4 ISF (25% total)
how much fluid and lytes are needed per day
4-2-1 rule
4 ml/kg/h for 1st 10kg
2 for next 10
1 for rest
def. effective osmole
particle that doesn’t cross cell membrane
- Na, K, glucose
- NOT ethanol and urea
what are 2 types of losses
sensible - those you feel - urine
insensible - those you don’t - sweat, resp
what is “free water” in 1 L of 70mmol/L fluid
500 ml is isotonic (140)
so 500ml is free
4 types of fluid loss
- pure water loss
- hypotonic
- isotonic
- blood
2 ways to lose free water
- . skin - insensible
- urine
- diabetes insipidus
- urea induced osmotic diuresis
3 ways to lose hypotonic
- skin
- sweat (20-50 Na) - urine
- most diuretics
- glucose or mannitol induced - GI
- vomiit
- diarrhea if due to osmotic laxative
4 ways to lose isotonic
- skin
- burns - GI
- most diarrhea
- ileus - urine
- thazides - third space losses
3 consequences of fluid loss
- hypovolemia
- less CO > hypotens> activate SNS - possible hypernatremia
- brain cells shrink> confusion - possibly lose other lytes
magnitude of blood volume lost for a liter loss of each type
- pure water loss - 80ml
- hypotonic - 80-250
- isotonic - 250-333
- blood- 1000ml
3 hormonal responses to hypovolemia
- SNS activation
- RAS activations
- ADH
effects of hormones (3)
- incr. CO
- vasoconstrict
- reduce urine loss and NaCl
4 Hx ways to assess loss
- urine (output, color)
- thirst/intake
- dizzy when standing
- direct evidence of loss
- blood, surg, GI etc