IV fluids Flashcards

1
Q

where is body water

A

1/3 ECF

2/3 ICF

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2
Q

where is water in ECF

A

1/4 plasma (8% total)

3/4 ISF (25% total)

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3
Q

how much fluid and lytes are needed per day

A

4-2-1 rule
4 ml/kg/h for 1st 10kg
2 for next 10
1 for rest

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4
Q

def. effective osmole

A

particle that doesn’t cross cell membrane

  • Na, K, glucose
  • NOT ethanol and urea
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5
Q

what are 2 types of losses

A

sensible - those you feel - urine

insensible - those you don’t - sweat, resp

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6
Q

what is “free water” in 1 L of 70mmol/L fluid

A

500 ml is isotonic (140)

so 500ml is free

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7
Q

4 types of fluid loss

A
  1. pure water loss
  2. hypotonic
  3. isotonic
  4. blood
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8
Q

2 ways to lose free water

A
  1. . skin - insensible
  2. urine
    - diabetes insipidus
    - urea induced osmotic diuresis
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9
Q

3 ways to lose hypotonic

A
  1. skin
    - sweat (20-50 Na)
  2. urine
    - most diuretics
    - glucose or mannitol induced
  3. GI
    - vomiit
    - diarrhea if due to osmotic laxative
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10
Q

4 ways to lose isotonic

A
  1. skin
    - burns
  2. GI
    - most diarrhea
    - ileus
  3. urine
    - thazides
  4. third space losses
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11
Q

3 consequences of fluid loss

A
  1. hypovolemia
    - less CO > hypotens> activate SNS
  2. possible hypernatremia
    - brain cells shrink> confusion
  3. possibly lose other lytes
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12
Q

magnitude of blood volume lost for a liter loss of each type

A
  1. pure water loss - 80ml
  2. hypotonic - 80-250
  3. isotonic - 250-333
  4. blood- 1000ml
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13
Q

3 hormonal responses to hypovolemia

A
  1. SNS activation
  2. RAS activations
  3. ADH
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14
Q

effects of hormones (3)

A
  1. incr. CO
  2. vasoconstrict
  3. reduce urine loss and NaCl
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15
Q

4 Hx ways to assess loss

A
  1. urine (output, color)
  2. thirst/intake
  3. dizzy when standing
  4. direct evidence of loss
    - blood, surg, GI etc
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16
Q

4 hemodynamic signs on Phx

A
  1. JVP
  2. postural hypotension
  3. postural rise in HR
  4. supine hypotens or BP
17
Q

5 other signs of low volume

A
  1. skin and mucous
    - tugor
    - cap refill
  2. urine
  3. weight loss
  4. CNS
    - confusion/coma
  5. head
    - fonanelle
    - sunken eyeballs
18
Q

what are three general levels of loss in adults1

A

mild - 1-2 liters
mod - 2-3
severe - 4-5

19
Q

fomula for free water deficit

A

[total body water x (plasma [Na] - 140)]/140

20
Q

how much water in man and woman

A

man 60%

woman 50%

21
Q

4 lab tests to help confirm hypovolemia

A
  1. urine
    - osmolarity rises - test specific gravity
  2. ratio of plasma urea:creatinine
    - rises to >8%
    - urea rises faster since reabsorbed with Na
  3. hematocrit/hemoglobin
    - compare to previous levels
  4. check for other lyte abnormalities
22
Q

3 indications of IV fluids

A
  1. existing large deficit
  2. anticipated large def.
  3. access to circulation for meds
23
Q

what are crystalloids and colloids

A

crystalloids - Saline/dextrose
colloids
- large mol. weight substances

24
Q

what happens when give saline

A
  • all stays in ECF

- no change in [Na]

25
Q

what happens when give dextrose

A

water goes 2/3 ICF, 1/3 ECF

[Na] down

26
Q

what happens when give half normal saline

A

half is like normal, half is like dextrose

27
Q

what is formula for change in plasma [Na] for giving a liter of fluid

A

(IV[Na] - patient [Na])/ (total body water +1)

28
Q

3 types of colloids

A
  1. abumin (5 and 25%)
  2. starch solutions
  3. fresh frozen plasma
29
Q

why give colloid

A

expect to stay in intravascular better

30
Q

4 steps to give fluids

A
  1. estimate and replace existing deficit
  2. replace ongoing def.
  3. reassess respnse to ther
  4. decide if additional are needed
31
Q

what to give if hypernatremic

A
  • may need free water
  • may also need isotonic
  • not too fast
32
Q

what to give if hyponatremic

A
  • avoid free water
33
Q

** mega important point about hypotonic fluids

A

don’t give to sick patients unless they are hypernatremic

- sick patients make ADH so don’t excrete free water

34
Q

4 possible routes

A
  1. periph vein IV
  2. central line
  3. intraosseous in kids
  4. continuous sub cut
35
Q

check cases

A

it’s shreiber