BPH and ED Flashcards

1
Q

Sx of storage issues

A
  • urgency
  • freq.
  • nocturia
  • urg incontinence
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2
Q

Sx of voiding issues

A
  • hestiancy
  • poor flow
  • intermmitency
  • straining
  • terminal dribble
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3
Q

post - voiding SX

A
  • dribble

- incomplete emptying

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4
Q

etiology of LUTS

A

multi-factorial, but we’ll concentrate on prostate

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5
Q

what are clinical features of BPH (2)

A

results from outlet obstuction and compensatory chances in detrusotr function

  1. voiding Sx
    - due to outflow obs
  2. storage Sx
    - due to detrusor overactivity
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6
Q

5 possible BPH complication

A
  1. retention
  2. incontinence
  3. hydronephrosis
  4. infection
  5. gross hematuria
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7
Q

6 parts of BPH work-up

A
  1. Hx and AUA score
  2. Phx - DRE
  3. urinalysis
  4. Cr to assess renal function
  5. PSA to rule out malig
  6. US for post-void resid
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8
Q

mgmt for mild Sx

A

watchful waiitng

- lifestyle changes

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9
Q

medical mgmt (3)

A
  1. a-blockers - -osins
    - relaxes smooth muscle
  2. 5-a reducase inhibs
    - blocks conversion to DHT to reverse growth
  3. tadalfl
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10
Q

when to refer

A
  • baseline abnormalities on tests
  • complications of BPH
  • not responding to therapy
  • pt pref
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11
Q

4 additional tests to do

A
  1. uroflowmetry
  2. cystoscopy
  3. urodynamics
  4. URT imaging
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12
Q

3 surgical Tx

A
  1. TURP
  2. open prostatectomy
  3. minimally invasive - laser
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13
Q

3 def. indications for surg

A
  1. refractory retention
  2. renal insufficiency
  3. intolerance/failure of meds
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14
Q

def. of ED

A

can’t get erection for 3 months

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15
Q

what is physiology of erection

A

stim>NO release> cGMP formation> smooth muscle relax> blood into sinusoids

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16
Q

3 major risks for ED

A
  1. age
  2. chronic disease
    - heart
    - diabetes
    - meds
  3. lifstyle
    - SMOKING - impairment of smooth muscle relaxation
17
Q

features of psycho erection

A
  • sudden onset
  • complete immediate loss
  • AM present
  • varies with ciricumstance
18
Q

features of organi

A
  • gradual onset

- etc

19
Q

3 main vascualr causes

A
  1. atherosclerosis - same risk factors
  2. venous leaks
  3. trauma
20
Q

6 neurogenic causes

A
  1. surgery
  2. cord injury
  3. MS or demylenating conditions
  4. DM
  5. mudendal nerve injurt
  6. stroke
21
Q

3 hormonal causes

A
  1. hypogonadism
  2. thyroid
  3. pit.
22
Q

6 types of meds

A
  1. antihypertensives
  2. SSRIs
  3. hormonal agents
  4. protease inhibs
  5. cytotoxic
  6. H2 agonists
23
Q

5 parts of SHIM

A
  1. confidence
  2. firmness
  3. freq
  4. completion/maintenance
  5. satisfaction
24
Q

4 first line therapies

A
  1. lifestye/drug mods
  2. psych
  3. androgen replacment
  4. oral therapy
25
Q

4 types of androgen replacement

A
  1. trandermal pathc
  2. IM injections
  3. sub-cut implant
  4. oral
26
Q

precautions for PDE-5s

A
  • cardiac disease
  • retinitis pigmentosa
  • protease inhibs
  • a-blockers
27
Q

3 second line Tx

A
  1. vacuum
  2. muse
  3. caverject
28
Q

3rd line

A

implant