Lung growth and defense Flashcards

1
Q

what rotates gut in development

A

cilia

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2
Q

where does gas ex happen at birth

A

alveolar ducts

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3
Q

age at which all alveoli are grown in # and size

A

8 and 15

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4
Q

what causes infant resp distress syndrome

A

surfactant defiency

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5
Q

what causes bronchopulmonary dysplasia

A

intubation/ventilation

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6
Q

are the lungs really sterile?

A

no, there is lots of unculturable bacteria

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7
Q

2 types of aquired lung defences

A
  1. humoral def.

2. pulmonary microbionme

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8
Q

4 functions of the nose

A
  1. warm/humidifies
  2. remove large particles
  3. anitoxidant
  4. absorbs soluble pollutnats
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9
Q

2 ways infections happen

A
  1. inspiration

2. aspiration

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10
Q

what normally prevents aspiration

A

epiglottis and vocal cords closing

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11
Q

3 causes of normal mechs. of aspiration prevention to fail

A
  1. depressed CNS
  2. muscle weakness
  3. esop disorders
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12
Q

what causes aspiration

A

infections caught in muscus and pulled into the lung

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13
Q

what sizes of particles get stuk where

A

> 8u get filtered out

2-4u are perfect to land in alveoli

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14
Q

size of bacteria and cig. particles

A

4u

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15
Q

what initiates a cough

A

particles touch upper airway and vagus sends signal

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16
Q

how is velocity increased in cough

A

high expiratory flow through a smaller trachea area

17
Q

3 ways to fuck the cough reflex

A
  1. narcotics
  2. decrease (abdo) muscle strength
  3. airway obstruction
18
Q

what are 2 layers of mucus and where produced?

A
  1. sol (bottom) - by goblets

2. gel (top) - mucus glands

19
Q

what happens in CF

A

Na/Cl transport deficiency leads to think mucus

20
Q

where do alveolar macrophages come from

A

blood monocytes

21
Q

what happens in AIDS

A

lack of immunity leads to recurrent lung infections

22
Q

what does one potentially lose in C-sections

A

aquired microbiome from mother