gas transport in blood Flashcards
what defines hypoxemia
state of low paO2
what carries the blood O2
98% Hb and the rest dissolved in plasma
what must O2 do before it can be bound by Hb
dissolve into plasma
what color are reduced and O2 Hb
reduced - blue
with O2 - red
what is normal arterial and venous pO2
atrerial - 90torr (sat 98%) venous 40torr (sat 75%)
how to increase 95% plus O2 Sat
trick! you can’t!
where on pO2/sat curve does uptake occur
on the steep part
4 factors that cause a Rward shift of O2 curve
- low pH
- high temp
- high 2,3 diphosophglyceride
- high CO2
what is the P50
the paO2 at which Hb is 50% saturated
what is normal P50
27 torr
what happens to P50 if curve is shifted to right
goes up
what happens in mutation causing Hb to have inreased affiinty for O2
shift left - no release at capils. > need to produce more EPO and more cells
***what happens to PaO2 in anemia
unchanged
what happens to O2 sat in anemia
unchanged
what happens to O2 content in anemia
drops
how does CO change O2 curve
makes it hyperbolic - and thus decreases delivery
what are three forms of CO2 in blood
- bicarb
- dissolved in plasma
- in carbaminoHb
where is most CO2 carried in blood
dissolved in plasma - 20x more soluble
how does CO2 help Hb release O2
makes red cell acid > lessens Hb affinity
what holds more CO2, reduced or O2 Hb?
reduced
what is shape of CO2 curve
linear
what is art./vein diff for CO2
7
what is art./vein diff for O2
50
