gas transport in blood Flashcards

1
Q

what defines hypoxemia

A

state of low paO2

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2
Q

what carries the blood O2

A

98% Hb and the rest dissolved in plasma

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3
Q

what must O2 do before it can be bound by Hb

A

dissolve into plasma

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4
Q

what color are reduced and O2 Hb

A

reduced - blue

with O2 - red

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5
Q

what is normal arterial and venous pO2

A
atrerial - 90torr (sat 98%)
venous 40torr (sat 75%)
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6
Q

how to increase 95% plus O2 Sat

A

trick! you can’t!

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7
Q

where on pO2/sat curve does uptake occur

A

on the steep part

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8
Q

4 factors that cause a Rward shift of O2 curve

A
  1. low pH
  2. high temp
  3. high 2,3 diphosophglyceride
  4. high CO2
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9
Q

what is the P50

A

the paO2 at which Hb is 50% saturated

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10
Q

what is normal P50

A

27 torr

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11
Q

what happens to P50 if curve is shifted to right

A

goes up

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12
Q

what happens in mutation causing Hb to have inreased affiinty for O2

A

shift left - no release at capils. > need to produce more EPO and more cells

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13
Q

***what happens to PaO2 in anemia

A

unchanged

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14
Q

what happens to O2 sat in anemia

A

unchanged

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15
Q

what happens to O2 content in anemia

A

drops

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16
Q

how does CO change O2 curve

A

makes it hyperbolic - and thus decreases delivery

17
Q

what are three forms of CO2 in blood

A
  1. bicarb
  2. dissolved in plasma
  3. in carbaminoHb
18
Q

where is most CO2 carried in blood

A

dissolved in plasma - 20x more soluble

19
Q

how does CO2 help Hb release O2

A

makes red cell acid > lessens Hb affinity

20
Q

what holds more CO2, reduced or O2 Hb?

A

reduced

21
Q

what is shape of CO2 curve

A

linear

22
Q

what is art./vein diff for CO2

A

7

23
Q

what is art./vein diff for O2

A

50