Autonomic drugs

Question 1

what is somatic nerve, transmitter, and receptor

Answer 1

motor nerve with no ganglia, Ach, Nm receptor on muscle

Question 2

what does ANS control (3)

Answer 2

1. smooth muscle
2. cardiac muscle
3. glandular secretions

Question 3

for SNS, what is path of transmission

Answer 3

brain>autonomic ganglia(close to cord)>Ach>nicotinic receptor on post-synaptic neuron>NE> andrenergic receptor (except sweat which is muscarinic) on end organ

Question 4

for PNS, what is path of transmission

Answer 4

brain>autonomic ganglia(close to organ)>Ach>nicotinic receptor on post-synaptic neuron>Ach> muscarinic receptor on end organ

Question 5

PNS function

Answer 5

1. slow heart
2. stim GI
3. wetness

Question 6

where a PNS preganglionic neurons

Answer 6

brainstem and S2-4

Question 7

cranial nerves with PNS (4)

Answer 7

3 (occulomotor), 7 (facial), 9 (glossopharengeal), 10 (vagus)

Question 8

what are SNS functions

Answer 8

1. increase heart rate
2. dilate bronchi
3. more sweating, but less other secretions

Question 9

where are preganglionic cells of SNS located

Answer 9

T1-L2

Question 10

what are potential neurotranmitter autonomic drug targets

Answer 10

1. synthesis
2. uptake/reuptake
3. storage
4. release
5. degradation
6. receptors