Coronary artery disease

Question 1

4 main arteries of heart and what they supply

Answer 1

L coronary - Lat
R cor - Med
LAD - ant
posteior - inferior

Question 2

5 things that happen to endothelial cells in artheriosclerosis

Answer 2

1. up - permiability
2. up - ionlfamation
3. up - leukocyte adhesion
4. down - vasodilation molecules
5. down - antithrombotic mechs

Question 3

5 systemic causes of endothelial dysfunction

Answer 3

1. hypertension
2. diabetes
3. dyslipidemia
4. smoking
5. systemica inflammation

Question 4

1 local cause of endo dysfunction

Answer 4

sheer stress

Question 5

what happens to artery in artheriosclerosis

Answer 5

fatty streaks in the smooth mnucles layer

Question 6

why can you have a big plaque with no symptoms

Answer 6

grows outwardly

Question 7

when during a heart beat does perfusion occur

Answer 7

diastole

Question 8

3 things that influence O2 demand in heart

Answer 8

1. rate
2. wall stress
3. contractility

Question 9

when stenosis become a problem

Answer 9

70-80% range

Question 10

what causes an unstable plaque

Answer 10

thinning of collagen due to inflammation

Question 11

what happens if thin collagen cap ruptures

Answer 11

thrombotic response

Question 12

what can be measured as a measure of MI and when do levels peak

Answer 12

troopnin - 2 days after

Question 13

what is difference between stable and unstable angina

Answer 13

plaque rupture