menstrual cycle and disorders of menstruation Flashcards
1
Q
4 phases of cycle
A
- follicular
- ovulatory
- luteal
- menstrual
2
Q
**what happens in follicular
A
thickening of endo due to estradiol
3
Q
**what is length of follicular
A
variable
4
Q
what is hormone feedback
A
rising FSH 2nd to inhibin A
- progressive increase in estradiol due to follicle
- begative feedback to FSH
- rising LH- positive feedback
5
Q
what happens to egg in follicular
A
- egg is surrounded by granulosa cells
- creates follicle
- selection of single large follicle supresses others
- aromatized androgens
6
Q
what happens in ovulation phase
A
- rising estradiol causes LH surge and prog. prod
- oocyte relases ~36 after surge
- surge last 48-72 hrs
7
Q
clinical signs of ovulation
A
- associated temp fall follwed by rise
- clear eggwhite mucus due to E
- maybe twinge of pain
- progesterone porduction - PMS
8
Q
what happens in luteal phase
A
- empty follicle collapses
- turns into corpus luteum - makes prog.
- CL dependent on LH
9
Q
** length if luteal phase
A
14 days FIXED
10
Q
what is effect of high estrdiol and prog
A
supresses FSH so no folliculogenesis
11
Q
what happens in menstruation phase
A
- if no preg- CL stops producing inhibin A and prog
- FSH and inhib B rise and stim estradiol and next cycle
- lack of prog. restrict spiral arteries and get period
12
Q
def. primary amen
A
lack of
- sec characteristics by age 14
- menses by 16
- menses by 4 years after breasts
- menses 1 year after pubes
13
Q
def. secondary amen
A
no menses for 6 months after having had 3
14
Q
6 aspects of compartemental workup
A
- hypothal
- pit
- thyroid
- adrenal
- ovary
- outflow tract
15
Q
4 issues with hypo
A
- CNS lesions
- anorexia, stress, female athlete
- kallman’s syndrome
- pregancy***
16
Q
3 issues with pit***
A
- proactinoma
- other lesion
- sheehan’s syndrome - shortly after birth went hypovolemic
