obst. lung disease - asthma Flashcards

1
Q

def. asthma

A

inflamm. disorder of the airway causing paroxysmal or persistant Sx such as dyspnea, chest tightness, cheeze, associated with variable airflow limitations

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2
Q

Sx of asthma

A
vary in time and severity
- breathlessnes
- chest tightness
- cough
- wheeze
worse at night
colds "go to chest"
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3
Q

2 predisposing factors

A
  1. atopy

2. genetics

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4
Q

3 causal factors

A
  1. allergens - indoor and outdoor

2. occupational

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5
Q

6 contributing facotrs

A
  1. air pollution
  2. diet
  3. BMI
  4. low birth weight
  5. resp infections
  6. smoking
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6
Q

steps to Dx

A
  1. Hx and Phx
  2. PFT
  3. evaluate airway responsiveness
    - exercise and methacholine challenge
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7
Q

what is seen on a PFT

A

low FEV1/FVC ratio

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8
Q

what is seen on PFT for diagnosis

A
  • increases FEV1> 12% after inhaling B-agonists

- decreased PEF>10% after 6 minutes of execise

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9
Q

what is QOL in asthma

A
  • 55% not well controlled

- goal should be for patient to lead a normal life

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10
Q

4 things to do when poorly controlled

A
  1. confirm diagnosis
  2. checkcompliance
  3. review tech.
  4. question exposures/env
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11
Q

5 parts to treatment strategy

A
  1. ID and avoid triggers
  2. acheive control with approp. meds
  3. monitor and adjust meds
  4. devise an action plan for exacerbations
  5. educate patients
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12
Q

what are B-agonists

A
  • B2 selective so not heart issues
  • small doses
  • to site of action
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13
Q

what are B-agonists for

A

short acting

- releivers

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14
Q

3 B-agonist formats

A
  1. inhalers
  2. nebulized
  3. oral
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15
Q

what is action of inhaled corticosteroids

A
  1. reduce inflammation in the broncioles

2. preventer of further damage

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16
Q

2 general safety issues in steroids

A
  1. local
    - candidiasis, dysphonia (cords)
  2. systemic
    - adrenal
    - bruising
    - cushing
17
Q

what is effect on height

A

not one

18
Q

when to start on ICS

A

ASAP - changes the natural Hx of the disease

19
Q

2 long acting B-agonists

A
  1. salmeterol

2. formoterol

20
Q

what is use of LABAs

A

not a monotherapy

- can help patients not be woken at night with their Sx

21
Q

what are pos. effects of LABAs

A
  • reduce SABA needs
  • less night Sx
  • improve QOL
  • incr. FEV1
  • less exacerbations
22
Q

5 parts of education

A
  1. review parameters of control
  2. understand roles for diff. meds
  3. written actions
  4. empower patients to change meds
  5. demonstrated benefits in terms of QOL