pulm. hypertension Flashcards
1
Q
def. pulm HT
A
- elevation of mean pulm art. pressure
- > 25 mmHg
- caused y probs anywhere in pulm circulation
2
Q
def. pulm. arterial hypertension
A
- narrowing of the small pulm arteries and arterioles
- lead to vasc. resisitance
- right heart >25mmHg, AND normal left heart
3
Q
5 anatomic sites for PHT
A
- pulm. artery
- pulm arteriole
- pulm caps
- pulm veins
- L heart
4
Q
NICE classification
A
5 groups
- arteriole (PAH) and veno-occlusive (PVOD)
- left heart
- resp diseases
- pulm arterey
- misc
5
Q
what are features of PAH
A
- idiopathic
- genetic
- drug and toxin induced
associated with - CT disease
- HIV
- portal HT
6
Q
epi of PAH
A
- rare
- F>M
- low survivial if not treated
7
Q
4 steps for diagnosis of pulm HT
A
- resp and cardiac Sx
- risk for PAH
- famHx, toxic drugs, CTD, HIV , liver disease - risk for other 4 types
- physical findings of pulm HT
8
Q
5 investigations of pulm HT
A
- look for resp disease
- walk test, PFT, CXR - look for underlying predisposing causes
- look for cardiac disease
- ECG - look for VTE disease
- measue pulm. pressures
9
Q
5 Tx for pulm HT
A
- treat underlying cause if one
- diuretics for R heart failure
- O2
- heart of lung transplant
- specific vasodilator therapy for PAH
10
Q
3 possible vasodilator therapies
A
- endothelin antagonsits
- PDE-5is
- prostacyclines
