SI LAB - Glossary 2

Question 1

used in the detection of antibodies involve in the blocking of agglutination of erythrocytes

Answer 1

hemagglutination-inhibition technique

Question 2

ruptured erythrocytes

Answer 2

hemolyzed

Question 3

a substance causing agglutination of red blood cells

Answer 3

hemagglutinin

Question 4

an antibody capable of causing the lysis of dissolution of red cells with the consequent release of hemoglobin

Answer 4

hemolysin

Question 5

the lysis of red blood cells by specific antibody and serum complement

Answer 5

hemolysis

Question 6

inflammation of liver caused by virus or other agent

Answer 6

hepatitis

Question 7

an antibody produced in response to one antigen that will react with a second antigen genetically unrelated antigen

Answer 7

heterophil antibody

Question 8

antigen that is broadly distributed in nature

Answer 8

heterophil antigen

Question 9

virus that caused AIDS

Answer 9

Human Immunodeficiency Virus (HIV)

Question 10

solution in which has a concentration greater than the system with which it is compared

Answer 10

hypertonic solution

Question 11

a process by which the activity of serum complement is nullified

Answer 11

inactivation

Question 12

acute infectious disease caused by Epstein-Barr virus characterized by fever, pharyngitis, and lymphadenopathy

Answer 12

infectious mononucleosis (IM)

Question 13

acute infectious disease in which there is a moderate leukocytosis due to abnormal mononuclear cells

Answer 13

infectious mononucleosis (IM)

Question 14

outside the body; observable in a test tube

Answer 14

In vitro

Question 15

observable in a test tube

Answer 15

in vitro

Question 16

within the living body

Answer 16

in vivo

Question 17

molecule that combines with specific complementary configurations of the binding agent (e.g. receptors, proteins, or antibody)

Answer 17

ligand

Question 18

creation of a stable preparation of a biologic material by rapid freezing and dehydration of the frozen product under high vacuum

Answer 18

lyophilization

Question 19

an antibody which causes dissolution or lysis of cells

Answer 19

lysin

Question 20

an antigen-antibody reaction in w/c the reactive effect of a particular antigen is nullified by a specific antibody

Answer 20

neutralization

Question 21

surface somatic antigen of bacteria

Answer 21

O antigen

Question 22

antibody that attaches to a cellular or particular antigen rendering it susceptible to phagocytosis

Answer 22

opsonin

Question 23

hemagglutination resulting from antibodies that are directed against antigens absorbed to their erythrocyte surface

Answer 23

passive hemagglutination

Question 24

liquid portion of unclotted blood

Answer 24

plasma

Question 25

weak or irregular antigen-antibody reaction occurring when a great excess of antigen is exposed to a serum containing a relatively low titer of antibody

Answer 25

postzone reaction

Question 26

an Ag-Ab rxn in w/c a soluble antigen is caused to settle out by the action of specific antibody (precipitin)

Answer 26

precipitation

Question 27

a negative or weak reaction occurring when serum containing an extremely high titer of antibody is exposed to a relatively small amount of antigen

Answer 27

prozone reaction

Question 28

failure of serologic reaction to occur in high concentration of antibody

Answer 28

prozone reaction

Question 29

clumping of cells caused by agents other than antibodies

Answer 29

pseudoagglutination

Question 30

an atom with an unstable nucleus that spontaneously emits radiation as it decays to a stable nucleus

Answer 30

radioisotope

Question 31

antibody-like substance produced by the body in response to certain types of tissue invasion and destruction

Answer 31

reagin

Question 32

found in varying small amounts normally, but is usually increased in syphilis, malaria, etc

Answer 32

reagin

Question 33

a progressively higher dissolution of a substance arranged in a definite sequence or series

Answer 33

serial dilution

Question 34

branch of biology which concerns itself with antigens and antibodies and their relationships

Answer 34

serology

Question 35

a condition wherein cells are coated with incomplete (blocking or univalent) specific antibody

Answer 35

sensitized

Question 36

the detection of a specific antibody in the serum of an individual in whom the antibody was previously undetectable

Answer 36

seroconversion

Question 37

fluid portion after the blood clots

Answer 37

serum

Question 38

special affinity between an antigen and its corresponding antibody

Answer 38

specificity

Question 39

an assay in which one of the reactant is bound to a surface

Answer 39

solid radioimmunoassay

Question 40

an enzyme that dissolves clots by converting plasminogen to plasmin

Answer 40

streptokinase

Question 41

thymus-derived lymphocyte responsible for cell-mediated hypersensitivity

Answer 41

T-lymphocyte (T-Cell)

Question 42

expression of the highest dilution of serum w/c gives a visible reaction

Answer 42

titer

Question 43

measurement of light transmitted through a suspension of particles

Answer 43

turbidimetry

Question 44

agglutination of red blood cells by a virus

Answer 44

viral hemagglutination

Question 45

antibody (or agglutinin) or hemagglutinin that is active at 37C but not at 4C

Answer 45

warm agglutinin

Question 46

reduction in the electrical charge of a red cell when it is suspended in a high ionic strength colloidal medium (albumin)

Answer 46

zeta potential