history of pharmacology Flashcards

1
Q

first antimicrobial drugs (magic bullet)

A

Ilya Metchnikoff

Paul Ehrlich

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2
Q

isolation and discovery of insulin and its application in the treatment of diabetes

A

Frederick Banting

John Macleod

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3
Q

Chemical transmission of nerve impulses (neurotransmitters)

A

Sir Henry Dale

Otto Loewi

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4
Q

Hormones of adrenal cortex, their structure and biological effects

A

Edward Kendall
Tadeus Reichstein
Philip Hench

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5
Q

antagonists that block biologically active amines, including the first antihistamine

A

Daniel Bovet

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6
Q

transmitters in the nerve terminals and the mechanism for storage release, and inactivation

A

Sir Bernard Katz
Ulf von Euler
Julius Axelrod

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7
Q

mechanisms of the action of hormones with regard to inhibition and stimulation of cyclic AMP

A

Earl Sutherland Jr.

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8
Q

Discovery of prostaglandins

Mechanism of action of aspirin that inhibits prostaglandin synthesis

A

Sune Bergstrom
Bength Samulsson
John Vane

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9
Q

development of the first beta-blocker, propanolol, and anticancer agents that block nucleic acid synthesis

A

Sir James Black
Gertrude ELion
George Hitchings

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10
Q

discovery of G proteins and the role of these proteins in signal transduction in cells

A

Alfred Gilman

Martin Rodbell

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11
Q

recognition of nitric oxide as a signaling molecule in the cardiovascular system

A

Robert Furchgott
Louis Ignarro
Ferid Murad

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12
Q

Role of dopamine in schizophrenia and signal transduction in the nervous system leading to long-term potentiation

A

Arvid Carlsson
Paul Greengard
Eric Kandel

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12
Q

Penicillin

A

Sir Alexander Fleming
Ernst Chain
Sir Howard Florey

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