history of pharmacology Flashcards
first antimicrobial drugs (magic bullet)
Ilya Metchnikoff
Paul Ehrlich
isolation and discovery of insulin and its application in the treatment of diabetes
Frederick Banting
John Macleod
Chemical transmission of nerve impulses (neurotransmitters)
Sir Henry Dale
Otto Loewi
Hormones of adrenal cortex, their structure and biological effects
Edward Kendall
Tadeus Reichstein
Philip Hench
antagonists that block biologically active amines, including the first antihistamine
Daniel Bovet
transmitters in the nerve terminals and the mechanism for storage release, and inactivation
Sir Bernard Katz
Ulf von Euler
Julius Axelrod
mechanisms of the action of hormones with regard to inhibition and stimulation of cyclic AMP
Earl Sutherland Jr.
Discovery of prostaglandins
Mechanism of action of aspirin that inhibits prostaglandin synthesis
Sune Bergstrom
Bength Samulsson
John Vane
development of the first beta-blocker, propanolol, and anticancer agents that block nucleic acid synthesis
Sir James Black
Gertrude ELion
George Hitchings
discovery of G proteins and the role of these proteins in signal transduction in cells
Alfred Gilman
Martin Rodbell
recognition of nitric oxide as a signaling molecule in the cardiovascular system
Robert Furchgott
Louis Ignarro
Ferid Murad
Role of dopamine in schizophrenia and signal transduction in the nervous system leading to long-term potentiation
Arvid Carlsson
Paul Greengard
Eric Kandel
Penicillin
Sir Alexander Fleming
Ernst Chain
Sir Howard Florey