BB LAB - Glossary of Terms Flashcards
fluid obtained from a cyst of a dog tapeworm which can be a source of P1 substance and there can be used to neutralize anti-P1
Hydatid cyst
nonpenetrating cryoprotective agent added to protect cells against damage
Hydroxyethyl starch (HES)
decrease in body temp
hypothermia
reaction of the body to respond and recognize foreign substances
immune response
immunologic rxn induced by initial exposure to antigens
primary immune response
immunologic reaction induced following a second exposure to an antigenq
secondary immune response
also known as anamnestic response
secondary immune response
sugar molecule that gives antigen its specificity or identifies it uniquely
immunodominant sugar
H antigen specificity, what is the immunodominant sugar
L-fucose
A antigen specificity, what is the immunodominant sugar
N-acetyl-D-galactosamine
B antigen specificity, what is the immunodominant sugar`
D-galactose
any substance capable of stimulating animmune response
immunogen
ability of an antigen to stimulate antibody response
immunogenicity
syn for antibody
immunoglobulin
study of blood-related antigens and antibodies
immunohematology
rare dominant gene that inhibits production of all Lutheran antigens
In Lu
presence of agglutination or hemolysis in compatibility testing
Incompatible
while fetus is in the uterus
in utero
in vitro reaction in w/c under certain condition of time and temperature allow antigen-antibody complex to occur
incubation
random behavior of genes on separate chromosomes inherited separately from each other
independent assortment
passingof one gene from each parent to offspring
independent segregation
transfusion administered to a fetus while still in the uterus
intrauterine transfusion
number of charged particles in solution
Ionic strength
gamma or electron treatment of cellular blood product to prevent transfusion associated graft-vs-host disease (TA-GVHD)
irradiation
yellow appearance of skin, sclera of eyes, and body secretions caused by inc bilirubin level
jaundice
condition due to inc in unconjugated bilirubin
kernicterus
test performed on maternal blood specimen to detect fetal maternal hemorrhage
kleihauer-betke acid elution test
ABO antibodies are present in plasma/serum when the corresponding ABO blood antigens are not present on erythrocytes
Landsteiner Law
combination of Ab and multivalent Ag to form cross links and result in visible agglutination rxn
Lattice formation
seed extract capable of agglutinating red cells carrying the corresponding antigen
lectin
agglutinate red cells with A1 antigen
Dolichus biflorus (anti-A1)
agglutinate red cells with H antigen
Ulex europaeus (anti-H)
agglutinate red cells with N antigen
Vicia graminea (anti-N)
agglutinate red cells with M antigen
Iberis amara (anti-M)
agglutinate red cells with T antigen
Arachis hypogea (anti-T)
agglutinate red cells with Tn antigen
Salvia sclaera (anti-Tn)
graph used to predict severity of HDN during pregnancy by evaluation of amniotic fluid
Liley Graph
Liley Graph zone
mild or no disease
Zone I
Liley Graph zone
Moderate disease
Zone II
Liley Graph zone
Severe and life-threatening hemolysis
Zone III
location of gene on chromosome
locus
condition of an abnormal presence of hmw immunoglobulins
macroglobulinemia
replacement of one or more blood volumes w/in 24 hour interval
massive transfusion
common drug used in treatment of hypertension
Methyl Dopa (Aldomet)
cause of positive DAT
Methyl Dopa (Aldomet)
type of agglutination pattern where a population of redcells has agglutinated and remainder of red cells are not agglutinated
Mixed Field Agglutination
manner by which a gene is passed from one gen to another
mode of inheritance
type of inheritance patterns
trait that appears when gene that has been inherited can be found in each gen occurs with equal frequency in males and females
ex. most blood group system
autosomal dominant
trait manifested by people who are homozygous for alleles
both parents who do not express the trait may be carrier or heterozygous for recessive allele
autosomal recessive
ex. Rh negative (dd), Lu (a-b-), Bombay phenotype
autosomal recessive
these are traits transmitted to all daughters of affected father but not to sons
sex-linked dominant
ex, Xg^a Blood group
sex-linked dominant
trait appears much more frequently in males than in females due to inheritance from carrier mothers
sex-linked recessive
ex. hemophilia A
sex-linked recessive
it is an antigen composed of several units or subpart such as Rho (D) antigen
Mosaic (Du variant)
D antigen w/ complete subpart
Rh ABCD
D antigen w/ missing A-subpart
Rh aBCD
D antigen w/ missing B-subpart
Rh AbCD
D antigen w/ missing C-subpart
Rh ABcD
D antigen w/ missing D-subpart
Rh ABCd
term for womanhaving borne more than one child
multiparous
malignant neoplasm of bm characterized by abnormal proteins in plasma and urine
multople myeloma
