BB LAB - Glossary IV Flashcards

1
Q

reciprocal of the highest dilution that shows a visible reaction

A

titer

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2
Q

inherited characteristic based from gene action

A

trait

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3
Q

administration of blood or its components intravenously

A

transfusion

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4
Q

type of transfusion

blood taken from a patient to be used for same patient

A

autologous transfusion

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5
Q

type of transfusion

transfer of blood directly from one person to another

A

direct transfusion

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6
Q

type of transfusion
used in infants with HDN, it refers to withdrawal of small volume of blood and subsequent replacement with compatible blood

A

exchange transfusion

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7
Q

type of transfusion

transfusion of blood stored in blood bag coming from a homologous donor

A

indirect transfusion

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8
Q

type of transfusion

blood tranfusion in utero

A

intrauterine transfusion

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9
Q

adverse rxn happening to a patient ff tranfusion of a unit of blood or its components

A

Transfusion reaction

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10
Q

batch test that includes ABO, Rh, and antibody screening test

A

Type and Screen (T/S)

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11
Q

set of guidelines developed to protect healthcare workers from exposure to infectious agents

A

universal precaution

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12
Q

vascular skin reaction commonly signalling allergic rxn

A

Urticaria (hives)

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13
Q

refers to type O and type AB individual s who are considered popularly as universal donor and universal recipient respectively

A

Universality concept

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14
Q

ability of red cell to survive in vivo after transfusion

A

viability

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15
Q

plasma cell dyscrasia characterized by excessive production of gamma M globulin

A

Waldenstrom’s macroglobulinemia

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16
Q

colorless crystalline compound widely used as an anticlotting drug

A

Warfarin

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17
Q

anticoagulant drug that acts by inhibiting synthesis of vitamin K dependent factors: II, VII, IX, X

A

Warfarin

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18
Q

meaning of warfarin

A

Wisconsin Alumni Research Foundation + (Coum)arin

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19
Q

examples (?) of warfarin

A

coumadin
panwarfin
sofarin

20
Q

refers to successive suspension of whole blood with NSS, centrifugation, and finally decanting completely the supernatant fluid. preferably done 3x to remove interfering substances w/c is present in plasma

A

washing

21
Q

widely used in preparation of red cell suspension

A

washing

22
Q

weaker variant of D-antigen that is detectable only through indirect antihuman globulin test

A

Weak D (D^u)

23
Q

classification of Weak D (D^u)

A

Acquired D^u, Hereditary D^u, D^u variant/Mosaic

24
Q

grade of Weak D (D^u)

A

high grade low grade

25
Q

grade of Weak D (D^u)

does not require AHG for detection

A

high grade

26
Q

AHG meaning

A

Antihemophilic globulin

27
Q

grade of Weak D (D^u)

requires AHG for detection

A

low grade

28
Q

thick gelatinous substance rich in hyaluronic acid that make up the matrix of the umbilical cord

A

Wharton’s jelly

29
Q

period of time when the disease is present but tested serologically negative

A

window period

30
Q

soluble haptenic forms of A and B antigens capable of neutralizing their corresponding antibodies

A

Witebsky substance

31
Q

blood group whose genes are located in the X-chromosome

A

Xg blood group

32
Q

what antigen is seen in greatest frequency among females than males

A

Xg^a

33
Q

net negative charge of red cell measured at the surface of shear; if it is reduced, red cells tend to become closer to each other and therefore easier to agglutinate

A

zeta potential

34
Q

rxn that is influenced by amount of Ag and Ab from the cell-serum mixture; presence of either prozone or postzone often leads to false negative result

A

Zonal reaction

35
Q

zone (zonal reaction)

zone of antibody excess (happens if more serum is added)

A

prozone

36
Q

zone (zonal reaction)

zone of antigen excess (happens if red cell suspension is too heavy)

A

postzone

37
Q

zone (zonal reaction)

zone of maximum or greatest rxn

A

Equivalence zone

38
Q

mixture of 0.1 M dithiothreitol (DTT) plus 0.1% cysteine-activated papain used to dissociate IgG molecules from erythrocytes showing a + DAT reaction

A

ZZAP

38
Q

For anti-a and anti-b what is the required potency

A

1:256

39
Q

LISS Meaning

A

Low Ionic Strength Saline solution

40
Q

Composition of LISS

A

0.2% NaCl in glycine

41
Q

If LISS is used, incubation period may be shortened to – mins

A

5-15 mins

42
Q

The lower the ionic strength, the — the rate of antibody association

A

Higher

43
Q

Polybrene is useful in ID of Ab in what blood group system

A

Kidd

44
Q

Former name of respiratory distress syndrome

A

Hyaline Membrane Disease