BB LAB - Glossary IV Flashcards
reciprocal of the highest dilution that shows a visible reaction
titer
inherited characteristic based from gene action
trait
administration of blood or its components intravenously
transfusion
type of transfusion
blood taken from a patient to be used for same patient
autologous transfusion
type of transfusion
transfer of blood directly from one person to another
direct transfusion
type of transfusion
used in infants with HDN, it refers to withdrawal of small volume of blood and subsequent replacement with compatible blood
exchange transfusion
type of transfusion
transfusion of blood stored in blood bag coming from a homologous donor
indirect transfusion
type of transfusion
blood tranfusion in utero
intrauterine transfusion
adverse rxn happening to a patient ff tranfusion of a unit of blood or its components
Transfusion reaction
batch test that includes ABO, Rh, and antibody screening test
Type and Screen (T/S)
set of guidelines developed to protect healthcare workers from exposure to infectious agents
universal precaution
vascular skin reaction commonly signalling allergic rxn
Urticaria (hives)
refers to type O and type AB individual s who are considered popularly as universal donor and universal recipient respectively
Universality concept
ability of red cell to survive in vivo after transfusion
viability
plasma cell dyscrasia characterized by excessive production of gamma M globulin
Waldenstrom’s macroglobulinemia
colorless crystalline compound widely used as an anticlotting drug
Warfarin
anticoagulant drug that acts by inhibiting synthesis of vitamin K dependent factors: II, VII, IX, X
Warfarin
meaning of warfarin
Wisconsin Alumni Research Foundation + (Coum)arin
examples (?) of warfarin
coumadin
panwarfin
sofarin
refers to successive suspension of whole blood with NSS, centrifugation, and finally decanting completely the supernatant fluid. preferably done 3x to remove interfering substances w/c is present in plasma
washing
widely used in preparation of red cell suspension
washing
weaker variant of D-antigen that is detectable only through indirect antihuman globulin test
Weak D (D^u)
classification of Weak D (D^u)
Acquired D^u, Hereditary D^u, D^u variant/Mosaic
grade of Weak D (D^u)
high grade low grade
grade of Weak D (D^u)
does not require AHG for detection
high grade
AHG meaning
Antihemophilic globulin
grade of Weak D (D^u)
requires AHG for detection
low grade
thick gelatinous substance rich in hyaluronic acid that make up the matrix of the umbilical cord
Wharton’s jelly
period of time when the disease is present but tested serologically negative
window period
soluble haptenic forms of A and B antigens capable of neutralizing their corresponding antibodies
Witebsky substance
blood group whose genes are located in the X-chromosome
Xg blood group
what antigen is seen in greatest frequency among females than males
Xg^a
net negative charge of red cell measured at the surface of shear; if it is reduced, red cells tend to become closer to each other and therefore easier to agglutinate
zeta potential
rxn that is influenced by amount of Ag and Ab from the cell-serum mixture; presence of either prozone or postzone often leads to false negative result
Zonal reaction
zone (zonal reaction)
zone of antibody excess (happens if more serum is added)
prozone
zone (zonal reaction)
zone of antigen excess (happens if red cell suspension is too heavy)
postzone
zone (zonal reaction)
zone of maximum or greatest rxn
Equivalence zone
mixture of 0.1 M dithiothreitol (DTT) plus 0.1% cysteine-activated papain used to dissociate IgG molecules from erythrocytes showing a + DAT reaction
ZZAP
For anti-a and anti-b what is the required potency
1:256
LISS Meaning
Low Ionic Strength Saline solution
Composition of LISS
0.2% NaCl in glycine
If LISS is used, incubation period may be shortened to – mins
5-15 mins
The lower the ionic strength, the — the rate of antibody association
Higher
Polybrene is useful in ID of Ab in what blood group system
Kidd
Former name of respiratory distress syndrome
Hyaline Membrane Disease
