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Botany > BB LAB - Glossary II > Flashcards

BB LAB - Glossary II Flashcards

1
Q

fusion of malignant and normal cell that produces large quantities of monoclonal antibodies

A

murine hybridoma

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2
Q

group of sugars found on rbc membrane attached to a protein backbone

A

NANA (Sialic acid)

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3
Q

major source of membrane’s net negative charge

A

NANA (Sialic acid)

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4
Q

relating to birth

A

natal

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5
Q

before birth

A

prenatal

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6
Q

after birth

A

postnatal

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7
Q

newborn infant up to 4 months of age

A

neonate

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8
Q

enzyme that cleaves sialic acid from rbc membrane

A

neuraminidase

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9
Q

also known as agglutination-inhibition

A

Neutralization

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10
Q

refers to absence of agglutination due to inability of an Ab to react with red cell antigen because of previously bound soluble substance

A

Neutralization

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11
Q

principle involved in saliva testing

A

Neutralization

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12
Q

basic building blocks of DNA composed of phosphate group, sugar group and base

A

nucleotide

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13
Q

any individual who fails to express any antigens on red cells

A

null phenotype

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14
Q

chemical compound formed by a small number of simple carbohydrate molecules

A

oligosaccharide chain

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15
Q

required temp in C by which the antibody is most reactive

A

optimum temperature

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16
Q

temp for IgM cold reactive antibody

A

1-6C/20-24C

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17
Q

IgG warm reacting antibody

A

37C

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18
Q

spontaneous clumping of rbc against a given serum

A

panagglutination

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19
Q

group O rgt RBC used for Ab ientification

A

panel cell

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20
Q

refers to a woman who had at least one pregnancy

A

primiparous

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21
Q

type of cold autoimmune hemolytic anemia in w/c a biphasic IgG Ab can be demostrated with anti-P specificity

A

Paroxysmal cold hemoglobinuria

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22
Q

D antigen thatis missing part of its typical antigenic structure

A

Partial D

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23
Q

refers to the chance that the alleged father is the biological father

A

Paternity index

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24
Q

diagrammatic chart for illustrating inheritance patterns of traits in a family study

A

Pedigree chart

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25
Q

detectable characteristics of genes

A

phenotype

26
Q

initial treatment of elevated bilirubin using lights

A

phototherapy

27
Q

extra blood sample collected during whole blood donation from a donor w/c is intended for serological test

A

pilot tube

28
Q

fibrinogen containing liquid portion of anticoagulated blood

A

plasma

29
Q

can be used as specimen for backward typing to detect antibodies however might present problem because it can bring about rouleaux formation

A

plasma

30
Q

plasma prepared from whole blood subjected to heavy spin wc allow sedimentation of PLT leaving a plasma almost free of PLT

A

platelet poor plasma

31
Q

plasma prepared from whole blood subjected to SOFT spin wc allow sedimentation of PLT leaving a plasma with high number of PLT

A

platelet rich plasma

32
Q

products that are transfused in patients suffering from hypovolemia (dec plasma volume) or indicated among burn and shock patients

A

plasma volume expander

33
Q

NSA meaning

A

normal serum albumin

34
Q

PPF meaning

A

plasma protein fraction

35
Q

NSA alb and globulin %

A

96% Alb + 4% Globulin

36
Q

PPF alb and globulin %

A

83% Alb + 17% Globulin

37
Q

Synthetic volume expanders

A

Crystalloids and Colloids

38
Q

plasma derived volume expanders

A

NSA and PPF

39
Q

Crystalloids [2]

A

Ringer’s Lactate (Na, Cl, K, Ca, lactate ions)

Normal Saline Solution (0.85%-0.9% NaCl)

40
Q

Colloids [2]

A

Dextran (6%-10%)

HES (Hydroethyl starch)

41
Q

inability of patient to respond favorably after PLT transfusion thus desired increment in PLT not achieved

A

PLT Refractoriness

42
Q

spontaneous agglutination of red cells by most normal adult sera regardless of blood group

A

polyagglutination

43
Q

blood group system showing several allelic forms therefore rendering more than one alternative phenotype

A

polymorphism

44
Q

refers to after child birth

A

postpartum

45
Q

refers to after tranfusion

A

posttransfusion

46
Q

relative strength of Ab present in given antiserum usually expressed in titer

A

potency

47
Q

any substance that enhances Ag-Ab interaction from a given cell-serum mixture w/c may be used to detect low-titered Ab in routine testing

A

potentiator

48
Q

0.2% in NaCl in glycine

A

LISS (Low Ionic Strength Saline Solution)

49
Q

this medium has lower ionic strength that increases rate of antibody association
incubation may be shortened to 5-15 min if this medium is used

A

LISS (Low Ionic Strength Saline Solution)

50
Q

positively charge polymer that reduces zeta potential by neutralizing the negative charge in red cell

A

polybrene

51
Q

useful in identification of Ab in Kidd blood group system

A

polybrene

52
Q

enhances Ab-Ag rxn by concentrating Ab in the mixture through water removal

A

Polyethylene glycol

53
Q

PEG meaning

A

Polyethylene Glycol

54
Q

refers to 2x2 grid used for gene combination

A

punnett square

55
Q

system of procedures that ensures a lab to operate with most minimal errors

A

quality assurance

56
Q

close monitoring of lab operations to allow maximum reliability of test result

A

quality control

57
Q

in transfusion medicine, this refers to a person who benefits and receives blood transfusion

A

recipient

58
Q

refers to the required speed in a given time to sediment particles from a fluid mixture

A

relative centrifugal force

59
Q

RCF value

A

1.118 x 10^5 x radius x (rpm)^2

60
Q

RCF meaning

A

Relative centrifugal force

Botany (324 decks)

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