HEMA 2 LEC - Cytotechnology Flashcards
Numeric abnormalities
– not a multiple of the haploid number
aneuploidy
ex of aneuploidy
ex. Trisomy, monosomy
– chromosome number higher than 46
polyploidy
ex of polyploidy
ex. Triploidy (3n), tetraploidy(4n) ,hypodiploid, hyperdiploid, high hyperdiploid
occurs after rearrangement of chromosomes
Structural Abnormalities
: portion of the chromosome is missing or deleted.
Deletions
Duplications:
portion of the chromosome is duplicated, resulting in extra genetic material.
In a _____, segments from two different chromosomes have been exchanged.
reciprocal translocation
A portion of the chromosome has broken off, turned upside down and reattached, therefore the genetic material is ..
Inversions:
Formed by the mirror image copy of a chromosome segment including the centromere.
Isochromosome:
A portion of a chromosome has broken off and formed a circle or ring.
Rings:
This can happen with or without loss of genetic material.
Rings:
technology that is used to analyse the physical and chemical characteristics of particles in a fluid as it passes through at least one laser.
flow cytometry
Cell components are fluorescently labelled and then excited by the laser to emit light at varying wavelengths.
flow cytometry
excitation happens by __ in FC
Laser
