MYCOVIRO - CH 61 book Flashcards
agents of superficial and subcutaneous mycoses
Dematiaceous (Melanized) Molds
Found everywhere (ubiquitous) and saprophytic
Dematiaceous (Melanized) Molds
nutrition of melanized mold
saprophytic nutrition
exist as plant pathogens
Dematiaceous (Melanized) Molds
Produce melanin resulting observable dark coloration
Dematiaceous (Melanized) Molds
CA of tinea nigra
Hortaea werneckii
superficial infection manifested by macular patches on the palm of the hand or sole of the foot
tinea nigra
superficial infection in which
Skin lesions are stained with silver nitrate staining
tinea nigra
skin lesions of tinea nigra are stained with
silver nitrate staining
CA of black piedra
Piedraia hortae
Infection of the hair, scalp and occasionally the axillary and pubic hair
black piedra
superficial infection known as Madura Foot
mycetoma
other name of mycetoma
madura foot
Chronic, granulomatous infection usually involving the lower extremities
mycetoma
mycetoma involves what body part
lower extremities
black piedra infects what body part (4)
hair, scalp and occasionally the axillary and pubic hair
white piedra infects what body part
palm of the hand or sole of the foot
mycetoma characterized by (3)
- swelling
- purplish discoloration
- Tumorlike deformities of the subcutaneous tissue and multiple sinus tracts that drain pus
containing yellow, white, red, or black granules (depends on infecting organism
2 types of mycetoma
actinomycotic
eumycotic
mycetoma caused by aerobic actinomycetes (Nocardia, Actinomadura and Streptomyces spp.)
Actinomycotic (bacterial) mycetoma
CA of Actinomycotic (bacterial) mycetoma (3)
Nocardia
Actinomadura
Streptomyces
Subcategories of eumycotic mycetoma
white grain mycetoma
black grain mycetoma
mycetoma caused by heterogeneous group of fungi that have septated hyphae
Eumycotic (fungal) mycetoma
CA of white grain mycetoma (4)
P. boydii
Acremonium
Fusarium
Scedosporium
most common CA of white grain mycetoma
Pseudollescheria boydii (
Pseudollescheria boydii is found where (3)
standing water, soil, sewage
CA of black grain mycetoma (3) EMC
Exophiala jeanselmei
Cuvularia
Madurella mycetomatis
Chronic fungal infection acquired through traumatic inoculation
Chromoblastomycosis
Chromoblastomycosis is acquired through
traumatic inoculation
Characterized by development of papule at the site of inoculation that spreads to form warty or
tumorlike lesions resembling cauliflower
Chromoblastomycosis
Chromoblastomycosis: tumorlike lesions resemble __
cauliflower
Chromoblastomycosis is characterized by development of ___
papule at site of inoculation
body parts involved in Chromoblastomycosis
feet, legs, may spread to other sites
microscopic determinant of chromoblastomycosis
sclerotic bodies
Copper-colored, septate cells resembling copper pennies
sclerotic bodies
sclerotic bodies causes __ of epidermis
hyperplasia
CA of chromoblastomycosis (3)
CPF
Cladosporidium/Cladophialophora spp.
Phialophora spp.
Fonsecaea spp.
Fungal brain abscess is formerly known as
cerebral chromoblastomycosis
cerebral chromoblastomycosis new name
fungal brain abscess
Fungal brain abscess now considered a type of
phaeohyphomycosis
General term for any infection caused by a dematiaceous organism
phaeohyphomycosis
infection which may be subcutaneous, localized or systemic
phaeohyphomycosis
CA of brain abscess (3)
Cladophialophora bantiana
Exophiala dermatitidis
Bipolaris
CA of sinusitis
(4) ABCE
Alternaria
Bipolaris
Exserohilum
Curvularia
CA of Mycotic keratitis amd endophthalmitis
E. dermatitidis, Bipolaris, Curvularia spp.
microscopic (lab dx)
observe dematiaceous hyphae and small budding yeast cells and/or hyphal
fragments
what superficial infection
Tinea nigra
Conidia are produced by annellophores, containing successive rings called annelides
H. werneckii
Colonies are olive to black, shiny and yeastlike
H. werneckii
Lab Dx
Microscopic: Infected hairs are examined in wet mounts using KOH
what superficial infection
Black piedra
nodules composed of cemented mycelium
Black piedra
Nodules contain spindle-shaped asci that has a filament at each pole and contains 2 to 8
aseptate ascospores
Black piedra
Does not sporulate on routine mycologic media
Piedraia hortae
P. hortae susceptible to
cycloheximide
susceptible to cycloheximide
Piedraia hortae
may produce red to brown pigment in culture
Piedraia hortae
Highly septate, dematiaceous hyphae with swollen intercalary cells
Piedraia hortae
Dark brown to black colonies with aerial mycelium
Piedraia hortae