MYCOVIRO - CH 60 of book part 2 Flashcards
Type of conidia of microsporum spp
-large, spindle-shaped, echinulate, rough-walled, septated
-
macroconidia
Type of conidia of microsporum spp
-small, club-shaped, born on hyphae
microconidia
most important cause of tinea capitis; anthropophilic
M. audouinii
infected hairs: yellow-green under Wood’s lamp
M. audouinii
colony: velvety aerial mycelium that is colorless to light gray to tan
M. audouinii
reverse side: salmon-pink to reddish brown
M. audouinii
terminal chlamydoconidia, antler (curved, freely branching) and raquet (enlarged, club-shaped) hyphae
M. audouinii
favic chandeliers, pectinate bodies
M. audouinii
does not grow on rice
M. audouinii
anthropophilic microsporum
M. audouinii
zoophilic microsporum
M. canis
causes ringworm infection in dogs and cats
M. canis
fluoresce bright yellow-green under Wood’s lamp
M. canis
small spores outside the hair (ectothrix)
M. canis
M. gypseum
growth on rice used to differentiate which Microsporum species
Audouinii (-) and canis (+)
- colony: granular or fluffy with feathered border, white to buff, lemon-yellow to yellow-orange fringe at
the periphery
M. canis
- reverse side: bright yellow
M. canis
- macroconidia: spindle-shaped, echinulate (with spiny projections), thick-walled and with curved ends
M. canis
- microconidia: rare, few
M. canis
- grows on rice
M. canis
geophilic microsporum
M. gypseum
does not fluoresce under Wood’s lamp
irregularly covered with arthroconidia
M. gypseum
- ectothrix infection: hair
M. canis
M. gypseum
- reverse side: orange to brownish
M. gypseum
macroconidia: thick-walled, large, ellipsoidal, with rounded ends, echinulate surface
M. gypseum
- colony: flat, irregularly fringed, coarse and powdery surface, buff or cinnamon color
M. gypseum
rapid-growing microsporum
canis and gypseum
ellipsoidal macroconidia
M. gypseum
spindle-shaped macroconidia
M. canis
thick-walled macroconidia
M. gypseum
- bamboo hyphae
M. ferruginum
_____ are typically identified in a host compromised by some underlying disease process, such as lymphoma, leukemia, diabetes mellitus, or another defect of the immune system.
Opportunistic fungal infections
- tissue invasive infections that occur in immunocompromised hosts
OPPORTUNISTIC MYCOSES
- common cause of tinea pedis and tinea cruris
E. floccosum
- susceptible to cold; specimens should not be refrigerated
E. floccosum
- calcofluor white or KOH: fine branching hyphae
E. floccosum
- colony: olive-green to khaki, dull orange-brown periphery, cottony white aerial mycelium
E. floccosum
- microconidia: absent
E. floccosum
- macroconidia: smooth, thin-walled, club-shaped (beaver-tail), multiseptate
E. floccosum
a fungus ball of the external auditory canal
otomycosis
(infection of the nail and sur- rounding tissue),
onychomycosis
causes disseminated infections: pulmonary or sinus fungus ball, allergic pulmonary aspergillosis, external otomycosis, mycotic keratitis, onychomycosis, sinusitis, endocarditis, CNS infection
Aspergillus spp.
Aspergillus may produce what substance
aflatoxin (hepatotoxin)
cause of fungus ball and otitis externa
A. niger
what aspergillus spp
from nasal cultures –> subsequent invasive aspergillosis
A. flavus
Hyaline, septate, monomorphic molds
may cause mycotic keratitis, disseminated fusariosis with fungemia and necrotic skin
lesions
recovered from respiratory tract secretions and skin
Fusarium spp.
Hyaline, septate, monomorphic molds
causes wound infection and oral thrush
Geotrichum candidum
Hyaline, septate, monomorphic molds
associated with disseminated infection, fungemia, subcutaneous lesions, and
esophagitis
Acremonium spp.
Hyaline, septate, monomorphic molds
may cause allergic bronchopulmonary penicilliosis or chronic allergic sinusitis
Penicillium spp.
Hyaline, septate, monomorphic molds
Associated with endophthalmitis, cutaneous infections and arthritis
Paecilomyces spp.
Hyaline, septate, monomorphic molds
Associated with arthritis
Paecilomyces spp.
Hyaline, septate, monomorphic molds
Associated with cutaneous infections
Paecilomyces spp.
endocarditis, fungemia and invasive disease
P. variotii
associated with onychomycosis, pulmonary infection, fungus ball and invasive fungal
disease
Scopulariopsis spp.
associated with fungus ball
Scopulariopsis spp.
associated with pulmonary infection
Scopulariopsis spp.
what to observe for opportunistic mycoses
observe septate hyphae with dichotomous branching; some may have rounded, thick-walled cells
Antigen-Protein assay:
targets antigens of Aspergillus spp.
Galactomannan assay
Antigen-Protein assay
detects antigens common to all clinically important fungi
Beta-glucan assay
susceptible to cycloheximide
Aspergillus spp.
most commonly recovered Aspergillus spp.
species most often seen in the clinical laboratory
A. fumigatus
Aspergillus spp. resistant to ampicillin B
A. terreus
A. terreus resistant to what antibiotic
ampicillin B
