SI LAB - Glossary 1 Flashcards

1
Q

removal of antibodies from serum by addition of red cells that possess the corresponding surface antigen

A

absorption

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2
Q

antigen that is not genetically determined and is sometimes transient

A

acquired antigen

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3
Q

immunity generated by actual production of antibody by the host in the presence of foreign antigen

A

active immunity

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4
Q

normal serum constituents that increase in the presence of infection, injury, trauma to tissues

A

acute phase proteins

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5
Q

a substance that can increase the specific antibody production to, or the degree of sensitization against antigen by increasing its size or length of survival in the circulation

A

adjuvent

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6
Q

a substance (usually injected with an antigen) that improves the immune response, either humoral or cellular, to the antigen

A

adjuvent

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7
Q

attachment of one substance to the surface of another, in particular, attachment of antibody to specific receptors on a cell surface

A

adsorption

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8
Q

collection into clumps of the cells or particles distributed in a fluid

A

agglutination

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9
Q

antibody capable of causing agglutination with surface antigens

A

agglutinin

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10
Q

an antigen agglutinated or clumped by an agglutinin

A

agglutinogen

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11
Q

system for activating complement beginning at C3 and do not involve a serologic reaction

A

alternative complement pathway

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12
Q

substance in the blood and the lymph serving as one of the active component on the process of cytolysis, the other components being the complement and the cells with antibodies

A

amboceptor

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13
Q

anti-sheep red blood cell antibody that causes hemolysis of sheep red cells in the presence of complement

A

amboceptor

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14
Q

globulin formed in response to exposure to an antigen

A

antibody (Ab)

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15
Q

also known as immunoglobulin

A

antibody (Ab)

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16
Q

any substance that oppose or counteract the action of a complement

A

Anticomplementary susbtance

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17
Q

any substance which, when introduced into the body, stimulates the formation of antibody

A

Antigen (Ag)

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18
Q

union of antibody with its homologous antigen

A

Antigen-antibody complex

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19
Q

an autoantibody directed against a component of the nucleus, commonly found in systemic lupus erythematosus (SLE)

A

Antinuclear antibody (ANA)

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20
Q

serum containing antibody

A

antiserum

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21
Q

an antibody produced against streptolysin O,

A

antistreptolysin O

22
Q

a hemolysin produced by Group A streptococci

A

antistreptolysin O

23
Q

ASO meaning

A

antistreptolysin O

24
Q

antibody produced against self antigen

A

autoantibody

25
Q

a molecule that behaves as a self antigen

A

autoantigen

26
Q

lymphocyte from the bursa of Fabricius or an immunoglobulin-forming cell

A

B-cell

27
Q

substance contained in beef erythrocytes, which is capable of absorbing the heterophil antibodies produced as a result of infectious mononucleosis (IM) and serum sickness

A

Beef erythrocyte (BE) antigen

28
Q

BE meaning

A

Beef erythrocyte

29
Q

a protein, not normally present in human blood, appears in a wide variety of inflammatory conditions

A

C-reactive protein

30
Q

characterized by their ability to react with the C-polysaccharide somatic substance of the pneumococci

A

C-reactive protein

31
Q

the major system of complement activation that involves all nine components of complement and is initiated by a serologic reaction

A

Classic complement pathway

32
Q

an agglutinin or hemagglutinin that is active at 4C but not at 37C

A

Cold agglutinin

33
Q

a humoral mechanism of nonspecific immune response consisting at least 14 components that proceed in a cascading sequence of activation resulting in a cell lysis

A

Complement

34
Q

fixation of binding of complement in a reaction with antigen and antibody

A

Complement Fixation

35
Q

monitors day to day accurate performance of the laboratory tests/analyses

A

Control

36
Q

a substance composed of extract from fresh beef hearts combined with lecithin and cholesterol

A

Cardiolipin Antigen

37
Q

a hemagglutination test that defines the characteristics of heterophil antibody by guinea pig and beef cell antigens

A

Davidsohn Differential Test

38
Q

most common procedure for the separation of mononuclear cells

A

Density gradient centrifugation

39
Q

separation of one substance from the other

A

dissociation

40
Q

a fluid medium containing antibodies deliberately removed from the red cells

A

eluate

41
Q

ligand assay in which the label is an enzyme and the binding reagent is an antibody

A

enzyme immunoassay

42
Q

point of dilution in a serologic reaction in which all the antigen and all the antibody are mutually involved in complexes

A

equivalence point

43
Q

a specific type of precipitation that occurs over a narrow range of antigen concentration

A

flocculation

44
Q

aggregation of colloidal particles in a serologic reaction

A

flocculation

45
Q

heterophil antibody that is stimulated by one antigen and reacts with unrelated surface antigen present on cells from different mammalian species

A

forssman antibody

46
Q

substance which absorbs the Forssman and serum sickness antibodies

A

Guinea pig kidney (GPK) antigen

47
Q

flagellar antigens of bacteria

A

H antigens

48
Q

agglutination or clumping of red blood cells by the antiserum

A

hemagglutination

49
Q

attachment of antibody to specific receptors on a cell surface

A

adsorption

50
Q

ANA meaning

A

antinuclear antibody