MYCOVIRO - CH 60 of book part 3 Flashcards
- colony: fluffy to granular, white to blue-green
A. fumigatus
- septate hyphae, short or long conidiophores with “foot cell” (T or L shaped) at the base
A. fumigatus
- thermotolerant (can withstand up to 45C)
A. fumigatus
ASPERGILLUS SPP.
- identified by the (2)
morphology or conidial heads
- conidiophore is coarsely roughened near the vesicle
A. flavus
- colony: yellow-green
A. flavus
- globose vesicles producing phialides directly from surface (uniserate) or from metulae, a primary row of cells (biserate)
A. flavus
- yellow-orange, elliptical or spherical conidia
A. flavus
- darkly pigmented, roughened spores (macroscopically)
A. niger
- hyaline and septate hyphae (microscopically)
A. niger
- colony: begins as yellow then develops black dotted surface as conidia is produced
A. niger
- reverse side (Aspergillus spp): buff or cream
A. niger
- long conidiophores
A. niger
- colony: tan, resembling cinnamon
A. terreus
- hemispherical vesicles, phialides covers the entire surface
A. terreus
- aleurioconidia: larger cells found on submerged hyphae
A. terreus
- globose to elliptical conidia in chains
A. terreus
- colony: fluffy to cottony, may be pink, purple, yellow, green (depending on species)
- hyphae are small and septate
FUSARIUM SPP.
- most common medium to induced sporulation of Fusarium
cornmeal agar:
for identification of Fusarium
potato dextrose agar
- colony: white to cream, yeastlike
- hyphae are septate with rectangular to cylindrical to barrel-shaped arthroconidia
GEOTRICHUM CANDIDUM
- initial colony: yeastlike
- mature colony: white to gray to rose or reddish-orange
- small septate hyphae, ellipitical, single-celled conidia
ACREMONIUM SPP.
- colony: green or blue-green, velvety to powdery because of conidia
PENICILLIUM SPP.
- hyphae are hyaline and septate, produce brushlike conidiophore
PENICILLIUM SPP.
- blunted phialides producing small oval conidia
PENICILLIUM SPP.
colony: velvety, tan to olive brown, somewhat powdery
PAECILOMYCES SPP.
lavender to pink colonies
P . lilacinus:
long, delicate, tapering phialides
PAECILOMYCES SPP.
- colony: initially appear white but becomes light brown and powdery
SCOPULARIOPSIS SPP.
- microscopically resembles a large Penicillium organism
SCOPULARIOPSIS SPP.
- hyaline and septate species of Scopulariopsis (2, both starts with b)
S. brevicaulis, S. brumptii
most systemic mycoses are mono- or dimorphic?
dimorphic
systemic mycoses often start at what locus?
pulmonary locus
systemic mycoses Acquired via
inhalation of infectious conidia
Blastomyces dermatitidis: blastomycosis
mixture of suppurative and granulomatous infection o
o
Blastomyces dermatitidis: blastomycosis
commonly found in North America
Blastomyces dermatitidis: blastomycosis
more common in men than women
Blastomyces dermatitidis: blastomycosis
San Juaquin Valley Fever / Dessert Rheumatism
Coccidioides immitis: coccidioidomycosis (asymptomatic and self-limited)
dissemination in Filipinos and African Americans
Coccidioides immitis: coccidioidomycosis (asymptomatic and self-limited)
asymptomatic and self-limiting systemic diseases (2)
B. dermatitidis
H. capsulatum
chronic, granulomatous infection, begins in lungs and invades the reticuloendothelial system
Histoplasma capsulatum: histoplasmosis
Cave disease, spelunker’s disease
Histoplasma capsulatum: histoplasmosis
found in soil rich in bird or bat guano
Histoplasma capsulatum: histoplasmosis
chronic, granulomatous infection (2)
H. capsulatum
P. brasiliensis
produces ulcerative lesions of the mucuous membrane (nasal and oral mucosa, gingivae and
conjunctivae)
lesions are ulcerative with serpiginous (snakelike) active border and crusted surface
Paracoccidioides brasiliensis: paracoccioidomycosis
South American Blastocycosis
Paracoccidioides brasiliensis: paracoccioidomycosis
mucosal lesions are an integral part of the disease process
maybe acquired through trauma to the oropharynx
Paracoccidioides brasiliensis: paracoccioidomycosis
focal cutaneous and mucocutaneous infection granulomatous, suppurative and necrotizing
Penicillium marneffei
associated with (Vietnamese) bamboo rat
Penicillium marneffei
endemic in Southeast Asia
opportunistic
Penicillium marneffei
chronic subcutaneous infection
Sporothrix schenckii: sporothricosis
“rose gardener’s disease”
Sporothrix schenckii: sporothricosis
type of sporotrichosis acquired through inhalation of spores
Pulmonary sporotrichosis
acquired through trauma to the hand, arm or leg
Sporothrix schenckii: sporothricosis
only rarely disemminated
Sporothrix schenckii: sporothricosis
begins as small, nonhealing ulcer on the index finger –> develops nodular lesions of skin –>
involvement of lymphatic channels and lymph nodes
Sporothrix schenckii: sporothricosis
