HEMA LEC 2 - Cell Populations in Diff Lineages Part II Flashcards

1
Q

Maturation sequence is less well defined

A

MEGAKARYOCYTIC LINEAGE

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2
Q

– first markers of megakaryocytic

differentiation

A

CD41, CD61

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3
Q

=represents early megakaryoblast

A

CD34+

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4
Q

B & T lymphocytes – derived from lymphoid progenitors that express ___ (3)

A

CD34, TdT and HLA-DR

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5
Q

earliest B cell markers (3)

A

CD19, cytoplasmic CD22, cytoplasmic CD79

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6
Q

specific immature B cell marker; eventually froms B cell receptor

A

Cytoplasmic μ chain

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7
Q

first markers of T cell lineage;

A

CD2, CD7, cytoplasmic CD3

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8
Q

can be present in NK cells with CD 56;

A

CD2, CD7, cytoplasmic CD3

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9
Q

can be used to detect NK cell derived neoplasms

A

CD2, CD7, cytoplasmic CD3

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