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Botany > Para Lec - Hemoflagellates Trypanosoma > Flashcards

Para Lec - Hemoflagellates Trypanosoma Flashcards

1
Q

location of trypanosoma brucei during febrile periods

A

circulating blood

lymph nodes

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2
Q

location of trypanosoma brucei during sleepingperiods

A

CSF

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3
Q

lab diagnosis of trypanosoma cruzi

A

xenodiagnosis

demonstratoon of trypomastigote in thin and thick smears

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4
Q

habitat of t.cruzi

A

RES, Cardiac muscle, CNS

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5
Q

Location of amastigote

A
  1. Amastigote – intracellular (spleen, reticuloendothelial cells, tissues, monocytes)
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6
Q

Location of epimastigote

A

vector?

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7
Q

Location of promastigote

A

develop in gut of vector

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8
Q

Location of trypomastigote

A

final host, in blood circulation

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9
Q

– infects cattle

A

Trypanosoma brucei brucei

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10
Q

TRANSMISSION (4)

T. b. gambiense/rhodisiense

A
  • Vector: Tse-tse fly (Common MoT)
  • Mechanical transmission: blood-sucking insect
  • Mother to child transmission
  • Blood transfusion
  • Accident infection (pricks)
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11
Q

what stage of african trypanosomiasis

• Characterized by swelling/ small papule from

A

Stage 1: Hemolymphatic Stage

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12
Q

– swelling of lymph nodes at posterior neck region or at the cervical vertebrae

A

Winterbottom’s sign

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13
Q

what stage of african trypanosomiasis

• Sleeping sickness stage (blood brain barrier is crossed)

A

Stage 2: Chronic meningoencephalitic

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14
Q

what stage of african trypanosomiasis
Signs and symptoms: personality change, mood swings, insomnia, daytime lethargy, environmental withdrawal, secondary infection (E.g. Pneumonia)

A

Stage 2: Chronic meningoencephalitic

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15
Q

• Specimen for african trypanosomiasis diagnosis

A

: blood, CSF, lymph node aspirate

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16
Q

lab diagnosis for african trypanosomiasis

Gold standard

A

microscopy

17
Q

treatment
first stage, for T. brucei rhodisiense
-urinary tract, allergic reactions (Side effects?)

A

• Suramin

18
Q

treatment
first stage, for T. brucei gambiense
-side effects more tolerated

A

Pentamidine

19
Q
  • most important prevention and control for african trypanosomiasis
A

Education and public awareness

20
Q

phase of american trypanosomiasis disease

– free of symptoms

A

intermediate phase

21
Q

phase of american trypanosomiasis disease

characterized by chagoma (local swelling, observed on site of inoculation) or skin irritation

A

acute phase

22
Q

phase of american trypanosomiasis disease

enlargement of esophagus

A

chronic phase

23
Q

phase of american trypanosomiasis disease

lesions on internal organs like heart, PNS, esophagus, colon

A

chronic phase

24
Q

phase of american trypanosomiasis disease

3 Mega:

A

severe/chronic phase

25
Q

what organs involved in 3 mega

A

megaesophagus
megacolon
megacardiomyopathy

26
Q

vectors of american trypanosomiasis

A

Vectors: Triatoma, Rhodnius, Panstrongylus

27
Q

transmission of american trypanosomiasis

A
  • Vectors: Triatoma, Rhodnius, Panstrongylus (Also known as kissing bug)
  • Ingestion of food contaminated with parasites
  • Blood transfusion
  • Fetal transmission (13% stillborn deaths per year in Brazil)
28
Q

acute phase of american trypanosomiasis begins

A

1 week after infection

29
Q

unilateral swelling of eyelids

A

Romana’s sign

30
Q

the stage of the parasite recovered in xenodiagnosis

A

epimastigote or metacyclic trypomastigote

31
Q

2 types of smear for lab diagnosis of american trypanosomiasis

A

wet smear

stained smear

32
Q

sx for stained smear of american trypanosomiasis

A

blood, csf

33
Q

prevention of american trypanosomiasis

A

vector control

34
Q

treatment of american trypanosomiasis

A

benznidazole

nifurtimox

35
Q

IS stage of trypanosomes to man

A

trypomastigote

36
Q

IS stage of trypanosomes to vector

A

trypomastigote

37
Q

diagnostic stage of trypanosomes

A

IS stage of trypanosomes to man

38
Q

vector of African trypanosomiasis

A

Glossina spp.

Botany (324 decks)

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