HEMA LEC 2 - Cell Populations in Diff Lineages

Question 1

granulocytic lineage

first morphologically recognizable cell

Answer 1

myeloblast

Question 2

granulocytic lineage

immature cell markers myeloblast

Answer 2

CD34, CD38, HLA-DR, stem cell factor CD117

Question 3

granulocytic lineage

panmyeloid markers of myeloblast

Answer 3

CD13, CD33

Question 4

CD of promyelocyte of granulocytic lineage

Answer 4

CD15

Question 5

granulocytic lineage
CD 16 is acquired
Density of CD13 increases

Answer 5

myeloid near band stage

Question 6

monocytic lineage

Earliest immunophenotype stage – gradual increase in density of ___ (3)

Answer 6

CD13, CD33, CD11b antigens

Question 7

monocytic lineage

antigens of promonocyte

Answer 7

CD15, CD14

Question 8

monocytic lineage

Bright expression of ___ (2) persists throughout maturation

Answer 8

CD 64 and HLA-DR antigen

Question 9

Do not express pan-hematopoietic marker CD45

Answer 9

ERYTHROID LINEAGE

Question 10

earliest erythroid marker of

ERYTHROID LINEAGE

Answer 10

CD71

Question 11

ERYTHROID LINEAGE
Density of this antigen increases starting from
the pronormoblast stage

Answer 11

CD71

Question 12

Density of CD71 erythroid lineage is down-regulated in

Answer 12

reticulocytes

Question 13

ERYTHROID LINEAGE
first appear at the basophilic
normoblast stage

Answer 13

Glycophorin A