MYCOVIRO - CH 59 Book Flashcards

1
Q

Except for disease caused by ___, humans are resistant to infections caused by fungi.

A

dimorphic fungi

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2
Q

Classification of Fungi based on Appearance of Colonies

moist, creamy, opaque, pasty colonies

A

yeasts

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3
Q

Classification of Fungi based on Appearance of Colonies

– fluffy, cottony, woolly or powdery colonies

A

Mold or Filamentous fungi

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4
Q

– exhibit either a yeast and filamentous forms

A

Dimorphic fungi

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5
Q

– when dimorphism is temperature dependent

A

Thermally dimorphic fungi

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6
Q

Thermally dimorphic fungi produce a mold form at what temp

A

25C – 30C

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7
Q

Thermally dimorphic fungi produce yeast form at what C

A

35-37C

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8
Q

– fungi that have more than one independent form or spore stage; not temperature dependent

A

Polymorphic fungi

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9
Q

4 Phyla

-includes organisms that produce sparsely septate hyphae

A

Zygomycota

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10
Q

Zygomycota

  • asexual reproduction by ?
  • sexual reproduction by ?
A

sporangiospores

zygospores

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11
Q

what phyla

ex. are Rhizopus, Mucor, Rhizomucor, Absidia, Cunninghamella

A

Zygomycota

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12
Q

what phyla
filamentous
produce true septate hyphae

A

ascomycota

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13
Q

asexual repro of ascomycota

A

conidia formation

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14
Q

sexual repro

A

ascopore

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15
Q

2 forms of ascomycota

A

teleomorph and anamorph

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16
Q

what phyla is ubiquitous in nature

A

ascomycota

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17
Q

– fungi that have different asexual forms of the same fungus

A

*Synanomorphs

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18
Q

sexual reproduction of basidiomycota

A

basidiopores

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19
Q

plant pathogens; rarely cause disease in humans

A

basidiomycota

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20
Q

-includes the smuts, rusts mushrooms, Cryptococcus neoformans complex

A

basidiomycota

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21
Q

– teleomorphic form of Cryptococcus neoformans

A

*Filobasidiella neoformans

22
Q

– lack a sexual reproductive cycle

-asexual reproduction through conidia

A
  1. Deuteromycota
23
Q

also called fungi imperfecti

A

Deuteromycota

24
Q

dimorphic fungus; has not been assigned to any phylum so it is placed in the order Incertae sedis

A

Blastomyces dermatitidis –

25
Q

in which order is Blastomyces dermatitidis assigned

A

Incertae sedis

26
Q

classification of fungi based on type of infection

A

superficial or cutaneous
deep or systemic
subcutaneous
opportunistic

27
Q

-involve the hair, skin, or nails without direct invasion of deeper tissue

A

superficial or cutaneous

28
Q

mycoses which all infect keratinized tissues

A

superficial or cutaneous

29
Q

– causes infection to the subcutaneous tissue only (no dissemination to other sites)

A

Subcutaneous mycoses

30
Q

examples are Chronomoblastomycosis, mycetoma, phaeohyphomycotic cysts

A

Subcutaneous mycoses

31
Q

most common opportunistic mycoses

A
  • Aspergillus
  • Candida
  • Cryptococcus
32
Q

– may cause deeply invasive phaeohyphomycoses (produce brown-pigmented structures)

A

*Dematiaceous fungi

33
Q

type of pathogen which occurs in immunocompromised host

-not always as virulent, may lead to subclinical disease

A

primary

34
Q

type of pathogen, almost any fungus present in the environment

A

opportunistic

35
Q

virulence factors (4)

A
  • Size (should be small to reach alveoli)
  • Ability to grow at 37C and neutral pH
  • Conversion of dimorphic fungi from mycelial form to corresponding yeast or spherule form in the host
  • Toxin production
36
Q

Many fungi have a primary focus in the lungs, thus ___ are almost always included among specimens selected for culture.

A

respiratory secretions

37
Q

antifungal agent

  • prevents overgrowth by rapidly growing molds
  • should be included in at least one of the culture media
A

cycloheximide

38
Q

amount of RT secretions for inoculation

A

0.5 ml

39
Q

CSF must be filtered through a __ um membrane filter attached to a sterile syringe

A

0.45 um

40
Q

CSF Specimen

If

A

1-drop aliquots

41
Q

CSF

Media should have no ____

A

antibacterial or antifungal agents

42
Q

if CSF processing is delayed, w

A
  • keep at room temperature

* or place in a 30C incubator

43
Q

Automated blood culture systems (3)

A
  • BACTEC
  • BacT/ALERT
  • VersaTREK
44
Q

lysis-centrifugation system

  • for dimorphic fungi from blood
  • optimal for H. capsulatum recovery and other filamentous fungi
A

ISOLATOR

45
Q

Isolator is optimal for ____ recovery and other filamentous fungi

A

H. capsulatum

46
Q

temp and incubation time for blood specime

A

optimal temperature: 30C and incubation time: 21 days

47
Q

-submitted for dermatophyte culture

A

Hair, Skin, Nail Scrapings

48
Q

hair, skin, nail obtained by

A

scraping

49
Q

hair, skin, nail obtained by scraping using

A

scalpel blade or microscope slide

50
Q

mycosel agar contains

A

cycloheximide and chloramphenicol