endocrine glands Flashcards
– stimulates growth of bones, muscles and organs by increasing gene expression
GH
-resists protein breakdown and favor fat breakdown during periods of starvation
GH
↓GH, young person, small but normally proportioned
PITUITARY DWARF
- ↑GH present before bones finish growing in length
- exaggerated bone growth
- abnormally tall
GIANTISM
↑GH after completion of bone growth in length
-abnormally large facial features and hands
GIANTISM
PERIODS OF INCREASED GH SECRETION
↑GH after completion of bone growth in length
-abnormally large facial features and hands
somatomedins
- influences part of the effect of GH
- similar in structures to insulin and can bind to insulin receptors
- secretion from tissues is increased by GH
insulin-like growth factors
- binds to MBR on cells in cortex of adrenal glands
- increases the secretion of cortisol/hydrocortisone
- required to keep adrenal cortex from degenerating
Adrenocorticotropic hormone (ACTH)
-bind to melanocytes in skin and increase skin pigmentation
Adrenocorticotropic hormone (ACTH)
– bind to MBR on cells of gonads
-regulate growth, development, and functioning of gonads
Gonadotropins
cause the ovulation of oocytes and secretion of estrogen and progesterone
luteinizing hormone
-stimulates interstitial cells of the testes to secrete testosterone
Interstitial Cell-stimulating hormone
stimulates development of follicles in ovaries and sperm cells
Follicle-stimulating hormone (FSH) –
binds to MBR in cells of breast
-helps promote development of breast during pregnancy
prolactin
-stimulates the production of milk following pregnancy
prolactin
binds to MBR on melanocytes
- causes MBR on melanocytes to synthesize melanin
- structure is similar to ACTH
Melanocyte-stimulating hormone (MSH)
- increases water reabsorption by kidney tubules (result: less water lost as urine)
- causes blood vessels to constrict
ADH VASOPRESSIN
– caused by lack of ADH secretion
-production of large amount of dilute urine
DIABETES INSIPIDUS
causes contraction of smooth muscle cells of uterus
-causes milk letdown from breasts of lactating women
OXYTOCIN
- made up of 2 lobes connected by isthmus
- lobes are located on each side of trachea
- one of the largest endocrine glands
- appears more red because it is highly vascular
- surrounded by a connective tissue capsule
THYROID GLAND
secrete hormone calcitonin
C Cells or parafollicular cells
enlargement of thyroid gland
-excess TSH
GOITER
– lack of thyroid hormones
HYPOTHYROIDISIM
– hypothyroidism in infants
-mental retardation, short stature, abnormally formed skeletal structure
cretinism
hypothyroidism in adults
-decreased metabolic rate, sluggishness, reduced ability to perform routine tasks
myxedema
elevated rate of thyroid hormone secretion
-metabolic rate, extreme nervousness, chronic fatigue
hyperthyroidism
• Graves disease – results when immune system produces abnormal proteins that are similar in structure and function to TSH
-often accompanied by exophthalmia (bulging of eyes)
graves disease